BDBM50505407 CHEMBL4436124

SMILES [H][C@]12Cc3c(nc(nc3N3CCOC[C@H]3C)-c3cnc(N)nc3)N1CCOC2

InChI Key InChIKey=QDNFQHRZXWGYKH-UHFFFAOYSA-N

Data  2 KI  2 IC50  7 Kd

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50505407   

TargetSerine/threonine-protein kinase mTOR(Human)
University of Basel

Curated by ChEMBL

LigandBDBM50505407(CHEMBL4436124)Copy SMILESCopy InChI

Affinity DataKi:  2.5nMAssay Description:Inhibition of alexa fluor 647-labeled kinase tracer 314 binding to recombinant human N-terminal GST-fused mTOR (1360 to 2549 residues) expressed in b...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/18/2021
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
University of Basel

Curated by ChEMBL

LigandBDBM50505407(CHEMBL4436124)Copy SMILESCopy InChI

Affinity DataKi:  536nMAssay Description:Inhibition of alexa fluor 647-labeled kinase tracer 314 binding to recombinant human full-length N-terminal His6-tagged p110alpha/p85alpha expressed ...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/18/2021
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL