BDBM50505410 CHEMBL4551080

SMILES [H][C@]12Cc3c(nc(nc3N3CCOC[C@H]3C)-c3cnc(N)cn3)N1CCOC2

InChI Key InChIKey=KUZSBKJSGSKPJH-UHFFFAOYSA-N

Data  2 KI  2 IC50  7 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50505410   

TargetTarget of rapamycin complex subunit LST8(Human)
University of Basel

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50505410BDBM50505410(CHEMBL4551080)
Affinity DataIC50: 60nMAssay Description:Inhibition of mTORC1 in human A2058 cells assessed as reduction in ribosomal protein S6 phosphorylation at Ser235/236 residues incubated for 1 hr by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed