BDBM50505429 CHEMBL4446578

SMILES [H][C@@]12Cc3c(nc(nc3N3CCOCC3)-c3cnc(N)cc3C(F)(F)F)N1CCCC2

InChI Key InChIKey=ROQYXPYWCLAQKK-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50505429   

TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM50505429(CHEMBL4446578)
Affinity DataIC50: 321nMAssay Description:Inhibition of mTORC2 in human A2058 cells assessed as reduction in PKB phosphorylation at S473 residues incubated for 1 hr by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed