BDBM50518930 CHEMBL4453061

SMILES Fc1ccc2ccnc(N3CCN(CCCNc4cc(=O)oc5CCOCc45)CC3)c2c1

InChI Key InChIKey=VZYVBNMAUUYIHP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50518930   

TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518930BDBM50518930(CHEMBL4453061)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA topoisomerase 4 subunit ParC assessed as reduction in decatenation of kinetoplast DNA incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518930BDBM50518930(CHEMBL4453061)
Affinity DataIC50: 5.90E+4nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA topoisomerase 4 subunit ParC assessed as reduction in decatenation of kinetoplast DNA incubated for 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed