BDBM50526790 CHEMBL4555799

SMILES Clc1cnc(N[C@H]2CCCNC2)nc1-c1c[nH]c2ccccc12

InChI Key InChIKey=XWKQZYOSWGEGIH-NSHDSACASA-N

Data  6 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50526790   

TargetCyclin-dependent kinase 2(Human)
Tianjin University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50526790(CHEMBL4555799)
Affinity DataIC50: >200nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 9(Human)
Tianjin University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50526790(CHEMBL4555799)
Affinity DataIC50: >200nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 7(Human)
Tianjin University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50526790(CHEMBL4555799)
Affinity DataIC50: <20nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 12(Human)
Syros Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50526790(CHEMBL4555799)
Affinity DataIC50:  29nMAssay Description:Inhibition of CDK12/cyclin K (unknown origin) using 5-FAM-labeled peptide as substrate in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Syros Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50526790(CHEMBL4555799)
Affinity DataKd:  0.330nMAssay Description:Binding affinity to full length CDK7 (1 to 346 residues) /N-terminal TEV cleavable 6His tagged full length cyclinH (1 to 323 residues) (unknown origi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Syros Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50526790(CHEMBL4555799)
Affinity DataIC50:  23nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin) using 5-FAM-labeled peptide as substrate in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Syros Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50526790(CHEMBL4555799)
Affinity DataIC50:  102nMAssay Description:Inhibition of CDK2/cyclin E1 (unknown origin) using 5-FAM-labeled peptide as substrate in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed