BDBM50564276 CHEMBL4776781

SMILES CC(=O)c1c(C)c2cnc(Nc3ccc(cc3)N3CCNCC3)nc2n2cc(nc12)C(C)(C)C

InChI Key InChIKey=QCXLRAYMDUWMRT-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50564276   

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50564276(CHEMBL4776781)
Affinity DataIC50:  221nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50564276(CHEMBL4776781)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused CDK4 (1 to 303 residues)/GST-tagged CyclinD3 (1 to 292 residues) expressed in baculo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50564276(CHEMBL4776781)
Affinity DataIC50:  204nMAssay Description:Inhibition of CDK7/cyclin H (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50564276(CHEMBL4776781)
Affinity DataIC50:  2.08E+3nMAssay Description:Inhibition of CDK1/cyclin B (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50564276(CHEMBL4776781)
Affinity DataIC50:  60nMAssay Description:Inhibition of CDK2/cyclin A2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50564276(CHEMBL4776781)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of human full-length N-terminal GST tagged CDK6 (1 to 326 residues)/GST-tagged cyclinD3 (1 to 292 residues) expressed in baculovirus expre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed