BDBM50564296 CHEMBL4791259

SMILES CC(C)c1cn2c(n1)c(C(C)=O)c(C)c1cnc(Nc3ccc4CNCCc4n3)nc21

InChI Key InChIKey=HKKFFWNWVBAQRC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50564296   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50564296(CHEMBL4791259)
Affinity DataIC50:  23nMAssay Description:Inhibition of human full-length N-terminal GST tagged CDK6 (1 to 326 residues)/GST-tagged cyclinD3 (1 to 292 residues) expressed in baculovirus expre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL
LigandPNGBDBM50564296(CHEMBL4791259)
Affinity DataIC50:  9.90nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused CDK4 (1 to 303 residues)/GST-tagged CyclinD3 (1 to 292 residues) expressed in baculo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed