BDBM50613350 CHEMBL5285928
SMILES N[C@@H](CCN(C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)S(=O)(=O)c1ccc(F)c(c1)[N+]([O-])=O)C(O)=O
InChI Key InChIKey=HJCPHTUCSUVWNC-KFAHYOAQSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50613350
TargettRNA (cytosine(38)-C(5))-methyltransferase(Human)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of full-length human DNMT2 expressed in bacteria using tRNA-Asp as substrate and 3H-SAM as cosubstrate by tritium incorporation assayMore data for this Ligand-Target Pair
TargettRNA (cytosine(38)-C(5))-methyltransferase(Human)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataKd: 1.73E+4nMAssay Description:Binding affinity to full-length human DNMT2 expressed in bacteria assessed as apparent dissociation constant by ITC methodMore data for this Ligand-Target Pair
TargettRNA (cytosine(38)-C(5))-methyltransferase(Human)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataKd: 1.12E+4nMAssay Description:Displacement of FTAD from full-length human DNMT2 expressed in bacteria incubated for 10 mins by MST assayMore data for this Ligand-Target Pair