BDBM50618195 CHEMBL5412548

SMILES COc1ccc(-c2csc(n2)-c2ccc(OC)cc2OC)c(OC)c1

InChI Key InChIKey=YXHUKYMJGBZBNB-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50618195   

TargetCytochrome P450 1B1(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50618195(CHEMBL5412548)
Affinity DataIC50: 1nMAssay Description:Inhibition of CYP1B1 (unknown origin) expressed in HEK293-T-REx cells co-expressing POR incubated for 1 hr by resorufin dye based plate reader analys...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCytochrome P450 1A1(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50618195(CHEMBL5412548)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of CYP1A1 (unknown origin) expressed in HEK293-T-REx cells co-expressing POR incubated for 1 hr by resorufin dye based plate reader analys...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCytochrome P450 4B1(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50618195(CHEMBL5412548)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP450 in pooled human liver microsomes in presence of NADPH measured every 3 mins for 120 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCytochrome P450 1A2(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50618195(CHEMBL5412548)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin) incubated for 10 mins in presence of NADPH by resorufin dye based fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCytochrome P450 3A4(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50618195(CHEMBL5412548)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) incubated for 1 hr in presence of NADPH and 7-BFC by fluorescence based analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed