BDBM50625974 CHEMBL5409280

SMILES Cc1nnc(o1)-c1ccc(cc1)-c1cc(F)c(F)c2CN([C@H](C3CC3)C(C)(C)O)C(=O)c12

InChI Key InChIKey=BCDTWPYNLQYQJL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50625974   

TargetCeramide glucosyltransferase(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50625974(CHEMBL5409280)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of GCS in human A-375 cell golgi body preparations using ceramide and UDP-glucose as substrate by UDP-Glo based luminometric analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCeramide glucosyltransferase(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50625974(CHEMBL5409280)
Affinity DataIC50: 7.30nMAssay Description:Inhibition of GCS in wild type HDF cells by LC-MS assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed