BDBM50625982 CHEMBL5394721

SMILES CN1Cc2cc(ccc2C1=O)-c1cccc2CN([C@H](C3CC3)C(C)(C)O)C(=O)c12

InChI Key InChIKey=CEHOCLCXVFQUEK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50625982   

TargetCeramide glucosyltransferase(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50625982(CHEMBL5394721)
Affinity DataIC50: 44nMAssay Description:Inhibition of GCS in human A-375 cell golgi body preparations using ceramide and UDP-glucose as substrate by UDP-Glo based luminometric analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCeramide glucosyltransferase(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50625982(CHEMBL5394721)
Affinity DataIC50: 46nMAssay Description:Inhibition of GCS in wild type HDF cells by LC-MS assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed