BDBM518731 US11117865, Compound ZL0590

SMILES FC(F)(F)c1ccc(NC(=O)Nc2ccc(cc2)S(=O)(=O)N2CCC[C@@H]2CN2CCOCC2)cc1

InChI Key InChIKey=ZPMULUKHFNMJPF-UHFFFAOYSA-N

Data  18 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 518731   

TargetBromodomain testis-specific protein [22-138](Human)
University Of Texas

US Patent
LigandPNGBDBM518731(US11117865, Compound ZL0590)
Affinity DataIC50: 2.35E+3nMAssay Description:Determine the binding ability of BRD4 compounds to bromodomains of BRD2 and BRD4. 96 well plate based commercial TR-FRET Assay kits (Cayman Chemical,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2022
Entry Details
Go to US Patent

TargetBromodomain testis-specific protein [22-138](Human)
University Of Texas

US Patent
LigandPNGBDBM518731(US11117865, Compound ZL0590)
Affinity DataIC50: 2.35E+3nMAssay Description:Determine the binding ability of BRD4 compounds to bromodomains of BRD2 and BRD4. 96 well plate based commercial TR-FRET Assay kits (Cayman Chemical,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2022
Entry Details
Go to US Patent