BDBM525749 US11174252, Compound 436

SMILES CC(C)N1CCOc2c(F)cc(cc12)-c1nc(Nc2ccc(cn2)N2CCC(CC2)N(C)C)ncc1F

InChI Key InChIKey=HCEVZIBGQRWFCG-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 525749   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nuvation Bio

US Patent
LigandPNGBDBM525749(US11174252, Compound 436)
Affinity DataIC50: 5.00E+3nMAssay Description:FMS: IC50 values of compounds against FMS kinase were determined by LanthaScreen™ Eu Kinase Binding Assay at Invitrogen (Life Technologies Grand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
Go to US Patent