BDBM525769 US11174252, Compound 456

SMILES CC(C)N1CCOc2c(F)cc(cc12)-c1nc(Nc2ccc3CN(CCc3c2)C(=O)CN(C)C)ncc1F

InChI Key InChIKey=JAMUFNNBMXMUIC-UHFFFAOYSA-N

Data  6 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 525769   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Nuvation Bio

US Patent

LigandBDBM525769(US11174252, Compound 456)Copy SMILESCopy InChI

Affinity DataIC50: 1.95E+4nMAssay Description:PI3Kδ: Briefly, this assay was conducted in buffer (Tris-HCl 40 mM (pH7.5), Orthovanadate 3 mM, MgCl2 20 mM, DTT 2 mM, CHAPS 0.05%, DMSO 1%). PI...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
4/3/2022
Entry Details
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