BDBM525809 US11174252, Compound 501

SMILES CCN1CCC(CC1)c1ccc(Nc2ncc(F)c(n2)-c2cc(F)c3OCCN(C(C)C)c3c2)nc1

InChI Key InChIKey=CPJXTPZMRAOYPN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 525809   

TargetCyclin-dependent kinase 6(Human)
Nuvation Bio

US Patent
LigandPNGBDBM525809(US11174252, Compound 501)
Affinity DataIC50:  5nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetCyclin-dependent kinase 4(Human)
Nuvation Bio

US Patent
LigandPNGBDBM525809(US11174252, Compound 501)
Affinity DataIC50:  2nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent