BDBM528077 N-i6-chloro-2-fluoro-3-methoxybenzyl)-1 -ii2-methylquinolin-6-yl)methyl)-1 H-1 ,2,3-triazole-4-carboxamide::US11180484, Example 14 from WO 013/111108

SMILES COc1ccc(Cl)c(CNC(=O)c2cn(Cc3ccc4nc(C)ccc4c3)nn2)c1F

InChI Key InChIKey=DFJBJVOVYHHCOV-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 528077   

TargetCoagulation factor XII(Human)
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM528077(N-i6-chloro-2-fluoro-3-methoxybenzyl)-1 -ii2-methy...)
Affinity DataIC50: 4.00E+4nMAssay Description:Factor XIIa inhibitory activity in vitro was determined using standard published methods (see e.g. Shori et al., Biochem. Pharmacol., 1992, 43, 1209;...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent