BDBM604283 US11661419, Example 32::US20230280220, Example 32

SMILES C[C@@H]1CN(CC(=O)N(C)c2cc3nc([nH]c3cc2C)-c2n[nH]c3C[C@@]4(C)C[C@H]4Cc23)C[C@@H](C)O1

InChI Key InChIKey=IEHAISZRBYBCJP-RANSCRDSSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 604283   

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandPNGBDBM604283(US11661419, Example 32 | US20230280220, Example 32)
Affinity DataIC50:  16nMAssay Description:1.0M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was sti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandPNGBDBM604283(US11661419, Example 32 | US20230280220, Example 32)
Affinity DataIC50:  16nMAssay Description:ITK activity was determined by measuring the effect of a test compound in an ITK enzyme assay. 1.0 M HEPES Buffer pH 7.5 solution was prepared as fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent