BDBM621136 3,5-difluoro-N-((3S,4S)-4- fluoropyrrolidin-3-yl)-6- (7- isopropoxyimidazo[1,2- a]pyridin-3-yl)pyridin-2- amine::US20230303563, Compound 207

SMILES CC(C)Oc1ccn2c(cnc2c1)-c1nc(N[C@H]2CNC[C@@H]2F)c(F)cc1F

InChI Key InChIKey=OCDYJTRAVKONSS-UHFFFAOYSA-N

Data  3 IC50  11 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 621136   

TargetReceptor-type tyrosine-protein kinase FLT3 [K663Q](Human)
Children'S Hospital Medical Center

US Patent
LigandPNGBDBM621136(3,5-difluoro-N-((3S,4S)-4- fluoropyrrolidin-3-yl)-...)
Affinity DataKd:  6nMAssay Description:Table 33 and 34: Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2023
Entry Details
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