BDBM6843 5-{2-[(2-hydroxyethyl)amino]ethyl}-18-methyl-3,13,18-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4(9),5,7,11(15),17(21),19,22-nonaene-12,14-dione::indolocarbazole deriv. 13h

SMILES Cn1ccc2ccc3c4[nH]c5c(CCNCCO)cccc5c4c4C(=O)NC(=O)c4c3c12

InChI Key InChIKey=BRGYPSBHCUNPNP-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 6843   

LigandPNGBDBM6843(5-{2-[(2-hydroxyethyl)amino]ethyl}-18-methyl-3,13,...)
Affinity DataIC50: 33nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2005
Entry Details Article
PubMed
LigandPNGBDBM6843(5-{2-[(2-hydroxyethyl)amino]ethyl}-18-methyl-3,13,...)
Affinity DataIC50: 10nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2005
Entry Details Article
PubMed
LigandPNGBDBM6843(5-{2-[(2-hydroxyethyl)amino]ethyl}-18-methyl-3,13,...)
Affinity DataIC50: 265nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2005
Entry Details Article
PubMed
LigandPNGBDBM6843(5-{2-[(2-hydroxyethyl)amino]ethyl}-18-methyl-3,13,...)
Affinity DataIC50: 6.12E+3nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2005
Entry Details Article
PubMed
LigandPNGBDBM6843(5-{2-[(2-hydroxyethyl)amino]ethyl}-18-methyl-3,13,...)
Affinity DataIC50: 95nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2005
Entry Details Article
PubMed