BDBM77080 US10093697, 11.::US9694018, 11

SMILES CCCCC1(CCC)CN(c2ccccc2)c2cc(SC)c(OCC(=O)N[C@@H](C(=O)N[C@@H](CC)C(O)=O)c3ccc(O)cc3)cc2S(=O)(=O)C1

InChI Key InChIKey=IQXGLAOJZLZEGK-RMGBUEETSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 77080   

TargetIleal sodium/bile acid cotransporter(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM77080(US10093697, 11. | US9694018, 11)
Affinity DataIC50:  0.150nMAssay Description:ISBT Hu HEK Uptake SPA 13203 IBAT HUM Ileal Bile Acid Transporter Human HEK Glycocholic acid Uptake Radiometric SPA Inhibitor IC50 Mean IC50 (nM) was...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Albireo

US Patent
LigandPNGBDBM77080(US10093697, 11. | US9694018, 11)
Affinity DataIC50:  0.150nMAssay Description:ISBT Hu HEK Uptake SPA 13203 IBAT HUM Ileal Bile Acid Transporter Human HEK Glycocholic acid Uptake Radiometric¿SPA Inhibitor IC50 Mean IC50 (nM) was...More data for this Ligand-Target Pair
In DepthDetails US Patent