BDBM8068 2-Anilino-4-(thiazol-5-yl)pyrimidine deriv. 39::2-Chloro-N4-[4-(2,4-dimethylthiazol-5-yl)pyrimidin-2-yl]-N1,N1-dimethylbenzene-1,4-diamine::2-chloro-4-N-[4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-yl]-1-N,1-N-dimethylbenzene-1,4-diamine::CS20

SMILES CN(C)c1ccc(Nc2nccc(n2)-c2sc(C)nc2C)cc1Cl

InChI Key InChIKey=FUDBRAFSKPGJJE-UHFFFAOYSA-N

Data  2 KI  5 Kd  2 Koff  2 Kon

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 8068   

LigandPNGBDBM8068(2-chloro-4-N-[4-(2,4-dimethyl-1,3-thiazol-5-yl)pyr...)
Affinity DataKi:  1.00E+3nM ΔG°:  -8.32kcal/moleT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 100 uM ATP/ [gamma-32P...More data for this Ligand-Target Pair
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Date in BDB:
3/13/2006
Entry Details Article
PubMed