BDBM85561 2-[4-(Phenylsulfonyl)-Phenyl}-thiazole-4-yl-methyl-sulfamide, 2a

SMILES NS(=O)(=O)NCc1csc(n1)-c1ccc(cc1)S(=O)(=O)c1ccccc1

InChI Key InChIKey=ZBCYYPLZTWIDDF-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 85561   

TargetCarbonic anhydrase 2(Human)
UniversitÀ

LigandPNGBDBM85561(2-[4-(Phenylsulfonyl)-Phenyl}-thiazole-4-yl-methyl...)
Affinity DataKi:  28nM ΔG°:  -10.3kcal/molepH: 7.4 T: 2°CAssay Description:Inhibition assay using human Carbonic anhydrase I and II and bovine carbonic anhydrase IV. More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCarbonic anhydrase 4(Bovine)
UniversitÀ

LigandPNGBDBM85561(2-[4-(Phenylsulfonyl)-Phenyl}-thiazole-4-yl-methyl...)
Affinity DataKi:  83nM ΔG°:  -9.65kcal/molepH: 7.4 T: 2°CAssay Description:Inhibition assay using human Carbonic anhydrase I and II and bovine carbonic anhydrase IV. More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCarbonic anhydrase 1(Human)
UniversitÀ

LigandPNGBDBM85561(2-[4-(Phenylsulfonyl)-Phenyl}-thiazole-4-yl-methyl...)
Affinity DataKi: >1.00E+3nM ΔG°: >-8.18kcal/molepH: 7.4 T: 2°CAssay Description:Inhibition assay using human Carbonic anhydrase I and II and bovine carbonic anhydrase IV. More data for this Ligand-Target Pair
In DepthDetails
PubMed