BDBM92445 Inhibitor, 10::US8691753, 105

SMILES NC(=O)[C@H](CCC(O)=O)NC(=O)CCc1ccc(cc1)-c1cc(cs1)-c1ccccc1

InChI Key InChIKey=KDDWLGBIYXTPJG-UHFFFAOYSA-N

Data  20 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 92445   

TargetMacrophage metalloelastase(Human)
French Alternative Energies and Atomic Energy Commission

LigandPNGBDBM92445(US8691753, 105 | Inhibitor, 10)
Affinity DataKi:  3.60nM ΔG°:  -11.5kcal/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2012
Entry Details Article
PubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Human)
French Alternative Energies and Atomic Energy Commission

LigandPNGBDBM92445(US8691753, 105 | Inhibitor, 10)
Affinity DataKi:  113nM ΔG°:  -9.47kcal/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2012
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
French Alternative Energies and Atomic Energy Commission

LigandPNGBDBM92445(US8691753, 105 | Inhibitor, 10)
Affinity DataKi:  203nM ΔG°:  -9.12kcal/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
French Alternative Energies and Atomic Energy Commission

LigandPNGBDBM92445(US8691753, 105 | Inhibitor, 10)
Affinity DataKi:  377nM ΔG°:  -8.76kcal/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
French Alternative Energies and Atomic Energy Commission

LigandPNGBDBM92445(US8691753, 105 | Inhibitor, 10)
Affinity DataKi:  603nM ΔG°:  -8.48kcal/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
French Alternative Energies and Atomic Energy Commission

LigandPNGBDBM92445(US8691753, 105 | Inhibitor, 10)
Affinity DataKi:  2.63E+3nM ΔG°:  -7.61kcal/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
French Alternative Energies and Atomic Energy Commission

LigandPNGBDBM92445(US8691753, 105 | Inhibitor, 10)
Affinity DataKi:  3.00E+3nM ΔG°:  -7.53kcal/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
French Alternative Energies and Atomic Energy Commission

LigandPNGBDBM92445(US8691753, 105 | Inhibitor, 10)
Affinity DataKi:  3.01E+3nM ΔG°:  -7.53kcal/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2012
Entry Details Article
PubMed
TargetStromelysin-2(Human)
French Alternative Energies and Atomic Energy Commission

LigandPNGBDBM92445(US8691753, 105 | Inhibitor, 10)
Affinity DataKi:  3.11E+3nM ΔG°:  -7.51kcal/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2012
Entry Details Article
PubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Human)
French Alternative Energies and Atomic Energy Commission

LigandPNGBDBM92445(US8691753, 105 | Inhibitor, 10)
Affinity DataKi:  4.20E+3nM ΔG°:  -7.62kcal/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2012
Entry Details Article
PubMed