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Found 47 Enz. Inhib. hit(s) with Target = 'Cysteine protease falcipain-3 [5-492]'
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50243232(CHEMBL486232 | GNF-PF-5434 | N-((S)-4-methyl-1-oxo...)
Affinity DataIC50:  21nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50157741(CHEMBL374508 | E-64 | E64)
Affinity DataIC50:  35nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50157741(CHEMBL374508 | E-64 | E64)
Affinity DataIC50:  75nMAssay Description:Inhibition of falcipain3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50157752(2-[2-(4-{[(2-carboxyphenyl)hydrazono]methyl}benzyl...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50157759(CHEMBL224803 | N-(4-(1H-tetrazol-1-yl)phenyl)-2-(1...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50157755(CHEMBL221833 | N'-(5-chloro-2-hydroxybenzylidene)-...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50157736(3-((5-(2,3-dihydroxybenzylideneamino)naphthalen-1-...)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50157738(4-((4-(2,4-dihydroxybenzylideneamino)-3-chlorophen...)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50157760(CHEMBL438659 | N2',N6'-bis(2-hydroxybenzylidene)py...)
Affinity DataIC50:  1.05E+4nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50183375(CHEMBL381093 | N2,N7-bis(furan-2-ylmethyl)-9H-fluo...)
Affinity DataIC50:  1.14E+4nMAssay Description:Inhibition of falcipain3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50157757(CHEMBL221991 | N1-((5-((3-oxo-5,6-dihydroimidazo[2...)
Affinity DataIC50:  1.18E+4nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50157754(CHEMBL436500 | methyl 2-(2-(2-(4,6-dimethylpyrimid...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50157753(CHEMBL222322 | N'-(1-(4-hydroxy-2-oxo-2H-chromen-3...)
Affinity DataIC50:  1.39E+4nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50183389(CHEMBL204491 | N-benzyl-3-(2-benzylcarbamoyl-ethyl...)
Affinity DataIC50:  1.88E+4nMAssay Description:Inhibition of falcipain3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50243177((S)-benzyl 2-oxo-1-(1-oxo-4-phenylbutan-2-yl)-1,2-...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50243178((S)-methyl 4-(3-(benzyloxycarbonyl)-2-oxopyridin-1...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50157749(2-hydroxy-N'-[(4-{[(2-hydroxybenzoyl)hydrazono]met...)
Affinity DataIC50:  2.78E+4nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50157748(1-(naphthalen-2-ylsulfonyl)-4-(propylsulfonyl)pipe...)
Affinity DataIC50:  2.96E+4nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50183397(CHEMBL440764 | ethyl 2-(2-(furan-2-ylmethylamino)-...)
Affinity DataIC50:  3.12E+4nMAssay Description:Inhibition of falcipain3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50183408(1-((1-(phenylsulfonyl)piperidin-4-yl)methyl)-3-tos...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of falcipain3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50183392(4-(5-(5-(morpholinosulfonyl)thiophen-2-yl)thiophen...)
Affinity DataIC50:  3.77E+4nMAssay Description:Inhibition of falcipain3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50183404(CHEMBL204035 | N'-((2-chloro-6-fluorobenzyloxyamin...)
Affinity DataIC50:  3.85E+4nMAssay Description:Inhibition of falcipain3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50183402(CHEMBL205056 | methyl 2-(2-(4-(4-chlorophenylsulfo...)
Affinity DataIC50:  4.92E+4nMAssay Description:Inhibition of falcipain3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50183382(5-Isoxazol-3-yl-thiophene-2-sulfonic acid (5-dimet...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of falcipain3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50157751(2-(4-hydroxy-6-propylpyrimidin-2-ylthio)-N-phenyla...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50157761(CHEMBL222708 | N'-(2,4-dihydroxybenzylidene)-2-(qu...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50157742(CHEMBL376232 | diethyl 2-(2-(naphthalen-1-ylcarbam...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50183371(CHEMBL204973 | N'-benzylidene-2-(3-((4-methylthiaz...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of falcipain3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50183398(1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-(4-(fura...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of falcipain3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50157747(CHEMBL222709 | N-(3-hydroxy-phenyl)-3-(3-hydroxy-p...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50157740(4-((2-(2,4-dihydroxybenzylideneamino)ethylimino)me...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50157758(CHEMBL224915 | N'-(2-oxoindolin-3-ylidene)-2-(5-ph...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50157746(CHEMBL374510 | N'-(4-(2-(4-fluorophenylamino)-2-ox...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50183385(CHEMBL203823 | N-(2-(furan-2-ylmethylthio)ethyl)-2...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of falcipain3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50157744((S)-2-(2,3-dihydrobenzo[b][1,4]dioxine-3-carboxami...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50157756((S)-3-(2-(4,6-bis(phenylamino)-1,3,5-triazin-2-yl)...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50157745((R)-3-(2-(4-(phenylamino)-6-(piperidin-1-yl)-1,3,5...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50183403(CHEMBL203801 | N'-(1-(2-(m-toluidino)-2-oxoethyl)-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of falcipain3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50157743(4-(4-(pyridin-3-yl)thiazol-2-ylamino)phenol | 4-{[...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50183386(2-(2-(4-chlorophenylsulfonyl)ethylthio)-N-(4-(prop...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of falcipain3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50157737(CHEMBL224916 | N'-(3,4-dihydroxybenzylidene)-2-(5-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50183396(2-[(4-fluorobenzyl)sulfonyl]-N'-[(thien-2-ylcarbon...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of falcipain3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50183376((N1',N6')-N1',N6'-bis(1-methyl-2-oxoindolin-3-ylid...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of falcipain3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50183405(4,6-dimethyl-N,N-bis(2-(phenylsulfonyl)ethyl)-1,3,...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of falcipain3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50183377(CHEMBL383231 | methyl 3-[(3-{[2-(methoxycarbonyl)t...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of falcipain3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50183390(5-((4-chlorobenzylsulfonyl)methyl)-3-(thiophen-3-y...)
Affinity DataIC50:  5.66E+4nMAssay Description:Inhibition of falcipain3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve

Curated by ChEMBL
LigandPNGBDBM50157739(CHEMBL426564 | N'-(2-oxo-1-(2-oxo-2-(phenylamino)e...)
Affinity DataIC50:  6.22E+4nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed