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Found 2322 Enz. Inhib. hit(s) with Target = 'Dipeptidyl peptidase 1'
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM138133(US8871783, 19)
Affinity DataKi:  0.900nM ΔG°:  -51.6kJ/molepH: 6.0 T: 2°CAssay Description:The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM138118(US8871783, 4)
Affinity DataKi:  2.10nM ΔG°:  -49.5kJ/molepH: 6.0 T: 2°CAssay Description:The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM138136(US8871783, 22)
Affinity DataKi:  2.20nM ΔG°:  -49.4kJ/molepH: 6.0 T: 2°CAssay Description:The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM138137(US8871783, 23)
Affinity DataKi:  2.90nM ΔG°:  -48.7kJ/molepH: 6.0 T: 2°CAssay Description:The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM138117(US8871783, 3)
Affinity DataKi:  3.20nM ΔG°:  -48.5kJ/molepH: 6.0 T: 2°CAssay Description:The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM138135(US8871783, 21)
Affinity DataKi:  3.60nM ΔG°:  -48.2kJ/molepH: 6.0 T: 2°CAssay Description:The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM138139(US8871783, 25)
Affinity DataKi:  4nM ΔG°:  -47.9kJ/molepH: 6.0 T: 2°CAssay Description:The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM138131(US8871783, 17)
Affinity DataKi:  4.20nM ΔG°:  -47.8kJ/molepH: 6.0 T: 2°CAssay Description:The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM138128(US8871783, 14)
Affinity DataKi:  13.4nM ΔG°:  -44.9kJ/molepH: 6.0 T: 2°CAssay Description:The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM138115(US8871783, 1)
Affinity DataKi:  13.7nM ΔG°:  -44.9kJ/molepH: 6.0 T: 2°CAssay Description:The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM138126(US8871783, 12)
Affinity DataKi:  14.9nM ΔG°:  -44.7kJ/molepH: 6.0 T: 2°CAssay Description:The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM138140(US8871783, 26)
Affinity DataKi:  16.7nM ΔG°:  -44.4kJ/molepH: 6.0 T: 2°CAssay Description:The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM138130(US8871783, 16)
Affinity DataKi:  17.1nM ΔG°:  -44.3kJ/molepH: 6.0 T: 2°CAssay Description:The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM138116(US8871783, 2)
Affinity DataKi:  17.3nM ΔG°:  -44.3kJ/molepH: 6.0 T: 2°CAssay Description:The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM138138(US8871783, 24)
Affinity DataKi:  21.9nM ΔG°:  -43.7kJ/molepH: 6.0 T: 2°CAssay Description:The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM138132(US8871783, 18)
Affinity DataKi:  27nM ΔG°:  -43.2kJ/molepH: 6.0 T: 2°CAssay Description:The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM138124(US8871783, 10)
Affinity DataKi:  35.8nM ΔG°:  -42.5kJ/molepH: 6.0 T: 2°CAssay Description:The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM138134(US8871783, 20)
Affinity DataKi:  37.9nM ΔG°:  -42.4kJ/molepH: 6.0 T: 2°CAssay Description:The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM138121(US8871783, 7)
Affinity DataKi:  39.3nM ΔG°:  -42.3kJ/molepH: 6.0 T: 2°CAssay Description:The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM138129(US8871783, 15)
Affinity DataKi:  41.9nM ΔG°:  -42.1kJ/molepH: 6.0 T: 2°CAssay Description:The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM138127(US8871783, 13)
Affinity DataKi:  61.7nM ΔG°:  -41.2kJ/molepH: 6.0 T: 2°CAssay Description:The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM138123(US8871783, 9)
Affinity DataKi:  62nM ΔG°:  -41.1kJ/molepH: 6.0 T: 2°CAssay Description:The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM138120(US8871783, 6)
Affinity DataKi:  64.1nM ΔG°:  -41.1kJ/molepH: 6.0 T: 2°CAssay Description:The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM138125(US8871783, 11)
Affinity DataKi:  72.8nM ΔG°:  -40.7kJ/molepH: 6.0 T: 2°CAssay Description:The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM138122(US8871783, 8)
Affinity DataKi:  104nM ΔG°:  -39.9kJ/molepH: 6.0 T: 2°CAssay Description:The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM138119(US8871783, 5)
Affinity DataKi:  177nM ΔG°:  -38.5kJ/molepH: 6.0 T: 2°CAssay Description:The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM50026017(2-Amino-N-(benzyl-cyano-methyl)-acetamide | CHEMBL...)
Affinity DataKi:  2.70E+3nMAssay Description:Compound was tested for Inhibition of Dipeptidyl aminopeptidase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Mus musculus)
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50147181(3-{[1-(2-Amino-acetylamino)-3-methyl-butyl]-hydrox...)
Affinity DataKi:  3.90E+4nMAssay Description:Compound was evaluated to inhibit cathepsin C (Dipeptidyl peptidase I) in non competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Mus musculus)
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50147182(3-{[1-(2-Amino-acetylamino)-3-methyl-butyl]-hydrox...)
Affinity DataKi:  4.00E+4nMAssay Description:Compound was evaluated to inhibit cathepsin C (Dipeptidyl peptidase I) in non competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Mus musculus)
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50147183(3-{[(2-Amino-acetylamino)-phenyl-methyl]-hydroxy-p...)
Affinity DataKi:  1.76E+5nMAssay Description:Compound was evaluated to inhibit cathepsin C (Dipeptidyl peptidase I) in non competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM50026018(2-Amino-N-(1-benzyl-3-methanesulfonyl-allyl)-aceta...)
Affinity DataKi:  1.80E+5nMAssay Description:Compound was tested for Inhibition of Dipeptidyl aminopeptidase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Mus musculus)
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50147185(3-{[1-(2-Amino-acetylamino)-3-phenyl-propyl]-hydro...)
Affinity DataKi:  1.87E+5nMAssay Description:Compound was evaluated to inhibit cathepsin C (Dipeptidyl peptidase I) in non competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Mus musculus)
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50147180(3-{[(2-Amino-acetylamino)-phenyl-methyl]-hydroxy-p...)
Affinity DataKi:  1.88E+5nMAssay Description:Compound was evaluated to inhibit cathepsin C (Dipeptidyl peptidase I) in non competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM50026015(4-(2-Amino-acetylamino)-5-phenyl-pent-2-enoic acid...)
Affinity DataKi:  2.20E+5nMAssay Description:Compound was tested for Inhibition of Dipeptidyl aminopeptidase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Mus musculus)
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50147184(3-{[1-(2-Amino-acetylamino)-3-phenyl-propyl]-hydro...)
Affinity DataKi:  3.12E+5nMAssay Description:Compound was evaluated to inhibit cathepsin C (Dipeptidyl peptidase I) in non competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Mus musculus)
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50147187(3-{[1-(2-Amino-acetylamino)-2-phenyl-ethyl]-hydrox...)
Affinity DataKi:  4.29E+5nMAssay Description:Compound was evaluated to inhibit cathepsin C (Dipeptidyl peptidase I) in non competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Mus musculus)
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM50147186(3-{[1-(2-Amino-acetylamino)-2-phenyl-ethyl]-hydrox...)
Affinity DataKi:  5.14E+5nMAssay Description:Compound was evaluated to inhibit cathepsin C (Dipeptidyl peptidase I) in non competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM50026027(2-(2-Amino-acetylamino)-3-phenyl-propionamide | CH...)
Affinity DataKi:  6.20E+6nMAssay Description:Compound was tested for Inhibition of dipeptidyl Dipeptidyl aminopeptidase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM201017(US9540373, 6 | US9879026, Example 6 | USRE47636, E...)
Affinity DataIC50:  0.200nMT: 2°CAssay Description:The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM201017(US9540373, 6 | US9879026, Example 6 | USRE47636, E...)
Affinity DataIC50:  0.200nMT: 2°CAssay Description:Assay conditions: The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM201017(US9540373, 6 | US9879026, Example 6 | USRE47636, E...)
Affinity DataIC50:  0.200nMAssay Description:Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 10 6007270). The substrate Gly-Arg-AMC was from Biotrend (Pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM50195247(CHEMBL3936580)
Affinity DataIC50:  0.251nMAssay Description:Inhibition of human recombinant DPP1 using Gly-Arg-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM50310682((S)-2-amino-N-((S)-1-cyano-2-(5-phenylthiophen-2-y...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM201014(US9540373, 3 | US9879026, Example 3 | USRE47636, E...)
Affinity DataIC50:  0.300nMT: 2°CAssay Description:The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM633586(N—((S)-1-cyano-2-(3-fluoro-4′-(pentafluoro-1...)
Affinity DataIC50:  0.300nMAssay Description:Recombinant human DPP1 enzyme (R&D Systems, Cat. No. 1071-CY) at a final concentration of 100 μg/mL was mixed with recombinant human cathepsin L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM201014(US9540373, 3 | US9879026, Example 3 | USRE47636, E...)
Affinity DataIC50:  0.300nMT: 2°CAssay Description:Assay conditions: The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM201014(US9540373, 3 | US9879026, Example 3 | USRE47636, E...)
Affinity DataIC50:  0.300nMAssay Description:Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 10 6007270). The substrate Gly-Arg-AMC was from Biotrend (Pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM50502619(CHEMBL4561264)
Affinity DataIC50:  0.398nMAssay Description:Inhibition of recombinant human DPPI using H-Gly-Arg-AFC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM201015(US9540373, 4 | US9879026, Example 4 | USRE47636, E...)
Affinity DataIC50:  0.400nMT: 2°CAssay Description:The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM201015(US9540373, 4 | US9879026, Example 4 | USRE47636, E...)
Affinity DataIC50:  0.400nMAssay Description:Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 10 6007270). The substrate Gly-Arg-AMC was from Biotrend (Pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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