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Found 32 Enz. Inhib. hit(s) with Target = 'Dipeptidyl peptidase 4 [K6R,T557I]'
TargetDipeptidyl peptidase 4 [K6R,T557I](Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM50228403((R)-8-(3-aminopiperidin-1-yl)-7-(but-2-ynyl)-3-met...)
Affinity DataIC50:  1nMAssay Description:The DPP-4 Drug Discovery Kit (Enzo Life Sciences International, Inc.) was used for the assay of inhibition of DPP-4 activity. The assay is based on t...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4 [K6R,T557I](Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM16285(2-({6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-di...)
Affinity DataIC50:  7nMAssay Description:The DPP-4 Drug Discovery Kit (Enzo Life Sciences International, Inc.) was used for the assay of inhibition of DPP-4 activity. The assay is based on t...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4 [K6R,T557I](Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM11162((1R)-3-oxo-3-[3-(trifluoroethyl)-5,6-dihydro[1,2,4...)
Affinity DataIC50:  11nMT: 2°CAssay Description:A 200-無 reaction system containing DPP-IV (Sigma), a test compound, and 25 mmol/L HEPES buffer (containing 140 mmol/L NaCl, 1% BSA, and 80 mmol/L Mg...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4 [K6R,T557I](Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM167935(1,5-Dimethyl-2-phenyl-4-(6-(phenylsulfonyl)tetrazo...)
Affinity DataIC50:  14nMT: 2°CAssay Description:A 200-無 reaction system containing DPP-IV (Sigma), a test compound, and 25 mmol/L HEPES buffer (containing 140 mmol/L NaCl, 1% BSA, and 80 mmol/L Mg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4 [K6R,T557I](Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM167938(1',5'-Dimethyl-2'-phenyl-5-(phenylsulf...)
Affinity DataIC50:  15nMT: 2°CAssay Description:A 200-無 reaction system containing DPP-IV (Sigma), a test compound, and 25 mmol/L HEPES buffer (containing 140 mmol/L NaCl, 1% BSA, and 80 mmol/L Mg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4 [K6R,T557I](Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM170166((R)-40)
Affinity DataIC50:  23.5nMAssay Description:DPP-IV inhibition was measured by DPP-IV inhibitor screening assay kit (Cayman Chemical Company, Item No. 700210) following the manufacturer's in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4 [K6R,T557I](Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM170168((R)-43)
Affinity DataIC50:  36.2nMAssay Description:DPP-IV inhibition was measured by DPP-IV inhibitor screening assay kit (Cayman Chemical Company, Item No. 700210) following the manufacturer's in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4 [K6R,T557I](Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM170169((S)-43)
Affinity DataIC50:  36.9nMAssay Description:DPP-IV inhibition was measured by DPP-IV inhibitor screening assay kit (Cayman Chemical Company, Item No. 700210) following the manufacturer's in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4 [K6R,T557I](Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM167943(3-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1Hpyraz...)
Affinity DataIC50: >50nMT: 2°CAssay Description:A 200-無 reaction system containing DPP-IV (Sigma), a test compound, and 25 mmol/L HEPES buffer (containing 140 mmol/L NaCl, 1% BSA, and 80 mmol/L Mg...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4 [K6R,T557I](Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM167944(1,5-Dimethyl-4-(3-methyl-1-phenyl-5-(phenylsulfony...)
Affinity DataIC50: >50nMT: 2°CAssay Description:A 200-無 reaction system containing DPP-IV (Sigma), a test compound, and 25 mmol/L HEPES buffer (containing 140 mmol/L NaCl, 1% BSA, and 80 mmol/L Mg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4 [K6R,T557I](Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM167936(1,5-Dimethyl-2-phenyl-4-(3-(phenylsulfonyl)benzo[4...)
Affinity DataIC50:  73nMT: 2°CAssay Description:A 200-無 reaction system containing DPP-IV (Sigma), a test compound, and 25 mmol/L HEPES buffer (containing 140 mmol/L NaCl, 1% BSA, and 80 mmol/L Mg...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4 [K6R,T557I](Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM167932(1,5-Dimethyl-2-phenyl-4-(6-(phenylsulfonyl)-[1,2,4...)
Affinity DataIC50:  107nMT: 2°CAssay Description:A 200-無 reaction system containing DPP-IV (Sigma), a test compound, and 25 mmol/L HEPES buffer (containing 140 mmol/L NaCl, 1% BSA, and 80 mmol/L Mg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4 [K6R,T557I](Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM170167((S)-40)
Affinity DataIC50:  108nMAssay Description:DPP-IV inhibition was measured by DPP-IV inhibitor screening assay kit (Cayman Chemical Company, Item No. 700210) following the manufacturer's in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4 [K6R,T557I](Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM167933(7-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyra...)
Affinity DataIC50:  112nMT: 2°CAssay Description:A 200-無 reaction system containing DPP-IV (Sigma), a test compound, and 25 mmol/L HEPES buffer (containing 140 mmol/L NaCl, 1% BSA, and 80 mmol/L Mg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4 [K6R,T557I](Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM166622((2-(2,4-Dichlorophenyl)imidazo[1,2-a]pyridin-3-yl)...)
Affinity DataIC50:  130nMAssay Description:The DPP-4 Drug Discovery Kit (Enzo Life Sciences International, Inc.) was used for the assay of inhibition of DPP-4 activity. The assay is based on t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4 [K6R,T557I](Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM166624((2-(o-Tolyl)imidazo[1,2-a]pyridin-3-yl)methanamine...)
Affinity DataIC50:  290nMAssay Description:The DPP-4 Drug Discovery Kit (Enzo Life Sciences International, Inc.) was used for the assay of inhibition of DPP-4 activity. The assay is based on t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4 [K6R,T557I](Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM167934(1,5-Dimethyl-2-phenyl-4-(2-phenyl-6-(phenylsulfony...)
Affinity DataIC50:  313nMT: 2°CAssay Description:A 200-無 reaction system containing DPP-IV (Sigma), a test compound, and 25 mmol/L HEPES buffer (containing 140 mmol/L NaCl, 1% BSA, and 80 mmol/L Mg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4 [K6R,T557I](Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM166623((2-(2,5-Dichlorophenyl)imidazo[1,2-a]pyridin-3-yl)...)
Affinity DataIC50:  650nMAssay Description:The DPP-4 Drug Discovery Kit (Enzo Life Sciences International, Inc.) was used for the assay of inhibition of DPP-4 activity. The assay is based on t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4 [K6R,T557I](Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM166627((7-Methyl-2-(p-tolyl)imidazo[1,2-a]pyridin-3-yl)me...)
Affinity DataIC50:  840nMAssay Description:The DPP-4 Drug Discovery Kit (Enzo Life Sciences International, Inc.) was used for the assay of inhibition of DPP-4 activity. The assay is based on t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4 [K6R,T557I](Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM166625((2-(4-Bromophenyl)imidazo[1,2-a]pyridin-3-yl)metha...)
Affinity DataIC50:  940nMAssay Description:The DPP-4 Drug Discovery Kit (Enzo Life Sciences International, Inc.) was used for the assay of inhibition of DPP-4 activity. The assay is based on t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4 [K6R,T557I](Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM167939(1',5'-Dimethyl-2,2'-diphenyl-5-(phenyl...)
Affinity DataIC50:  1.64E+3nMT: 2°CAssay Description:A 200-無 reaction system containing DPP-IV (Sigma), a test compound, and 25 mmol/L HEPES buffer (containing 140 mmol/L NaCl, 1% BSA, and 80 mmol/L Mg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4 [K6R,T557I](Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM166621((2-(4-Chlorophenyl)imidazo[1,2-a]pyridin-3-yl)meth...)
Affinity DataIC50:  6.46E+3nMAssay Description:The DPP-4 Drug Discovery Kit (Enzo Life Sciences International, Inc.) was used for the assay of inhibition of DPP-4 activity. The assay is based on t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4 [K6R,T557I](Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM166626((6-Methyl-2-(p-tolyl)imidazo[1,2-a]pyridin-3-yl)me...)
Affinity DataIC50:  7.46E+3nMAssay Description:The DPP-4 Drug Discovery Kit (Enzo Life Sciences International, Inc.) was used for the assay of inhibition of DPP-4 activity. The assay is based on t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4 [K6R,T557I](Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM167931(1,5-dimethyl-2-phenyl-4-(2-(phenylsulfonyl)acetyl)...)
Affinity DataIC50:  1.01E+4nMT: 2°CAssay Description:A 200-無 reaction system containing DPP-IV (Sigma), a test compound, and 25 mmol/L HEPES buffer (containing 140 mmol/L NaCl, 1% BSA, and 80 mmol/L Mg...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4 [K6R,T557I](Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM166619((2-Phenylimidazo[1,2-a]pyridin-3-yl)methanamine hy...)
Affinity DataIC50:  1.37E+4nMAssay Description:The DPP-4 Drug Discovery Kit (Enzo Life Sciences International, Inc.) was used for the assay of inhibition of DPP-4 activity. The assay is based on t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4 [K6R,T557I](Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM167937(4-(8,10-Dimethyl-3-(phenylsulfonyl)pyrido[2',3...)
Affinity DataIC50:  1.45E+4nMT: 2°CAssay Description:A 200-無 reaction system containing DPP-IV (Sigma), a test compound, and 25 mmol/L HEPES buffer (containing 140 mmol/L NaCl, 1% BSA, and 80 mmol/L Mg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4 [K6R,T557I](Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM167940(6-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1Hpyraz...)
Affinity DataIC50:  1.73E+4nMT: 2°CAssay Description:A 200-無 reaction system containing DPP-IV (Sigma), a test compound, and 25 mmol/L HEPES buffer (containing 140 mmol/L NaCl, 1% BSA, and 80 mmol/L Mg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4 [K6R,T557I](Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM167941(Ethyl 6-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1...)
Affinity DataIC50:  1.76E+4nMT: 2°CAssay Description:A 200-無 reaction system containing DPP-IV (Sigma), a test compound, and 25 mmol/L HEPES buffer (containing 140 mmol/L NaCl, 1% BSA, and 80 mmol/L Mg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4 [K6R,T557I](Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM167942(Ethyl 6-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1...)
Affinity DataIC50:  1.83E+4nMT: 2°CAssay Description:A 200-無 reaction system containing DPP-IV (Sigma), a test compound, and 25 mmol/L HEPES buffer (containing 140 mmol/L NaCl, 1% BSA, and 80 mmol/L Mg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4 [K6R,T557I](Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM166628((8-Methyl-2-(p-tolyl)imidazo[1,2-a]pyridin-3-yl)me...)
Affinity DataIC50: >5.00E+4nMAssay Description:The DPP-4 Drug Discovery Kit (Enzo Life Sciences International, Inc.) was used for the assay of inhibition of DPP-4 activity. The assay is based on t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4 [K6R,T557I](Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM166620((2-(3-Chlorophenyl)imidazo[1,2-a]pyridin-3-yl)meth...)
Affinity DataIC50: >5.00E+4nMAssay Description:The DPP-4 Drug Discovery Kit (Enzo Life Sciences International, Inc.) was used for the assay of inhibition of DPP-4 activity. The assay is based on t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4 [K6R,T557I](Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM166629(Methyl 3-(aminomethyl)-2-(p-tolyl)imidazo[1,2-a]py...)
Affinity DataIC50: >5.00E+4nMAssay Description:The DPP-4 Drug Discovery Kit (Enzo Life Sciences International, Inc.) was used for the assay of inhibition of DPP-4 activity. The assay is based on t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed