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Found 5 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor [696-1210,T790M]'
TargetEpidermal growth factor receptor [696-1210,T790M](Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society

LigandPNGBDBM4567(4-anilinoquinazoline deriv. 2 | BMC163482 Compound...)
Affinity DataIC50:  1.20nMpH: 7.5 T: 2°CAssay Description:The kinase reaction for EGFR consisted of BSA-supplemented kinase buffer, kinase, peptide, and ATP. For IC50 determinations, 10 different concentrati...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [696-1210,T790M](Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society

LigandPNGBDBM4583((2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4...)
Affinity DataIC50:  3nMpH: 7.5 T: 2°CAssay Description:The kinase reaction for EGFR consisted of BSA-supplemented kinase buffer, kinase, peptide, and ATP. For IC50 determinations, 10 different concentrati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor [696-1210,T790M](Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society

LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataIC50:  260nMpH: 7.5 T: 2°CAssay Description:The kinase reaction for EGFR consisted of BSA-supplemented kinase buffer, kinase, peptide, and ATP. For IC50 determinations, 10 different concentrati...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [696-1210,T790M](Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society

LigandPNGBDBM31826(4-aminoquinazoline, 2a | BMC163482 Compound 3 | CH...)
Affinity DataIC50:  360nMpH: 7.5 T: 2°CAssay Description:The kinase reaction for EGFR consisted of BSA-supplemented kinase buffer, kinase, peptide, and ATP. For IC50 determinations, 10 different concentrati...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [696-1210,T790M](Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society

LigandPNGBDBM102620(BMX-IN-1 | N-[5-[9-[4-(methanesulfonamido)phenyl]-...)
Affinity DataIC50:  4.28E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed