| Entry |
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| Symbol |
ELANE, ELA2, GE, HLE, HNE, NE, PMN-E, SCN1
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| Name |
(RefSeq) elastase, neutrophil expressed
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| KO |
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| Organism |
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| Pathway |
| hsa04613 | Neutrophil extracellular trap formation |
| hsa05202 | Transcriptional misregulation in cancer |
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| Network |
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| Element |
| N00118 | TEL-AML1 fusion to transcriptional repression |
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| Disease |
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| Drug target |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09150 Organismal Systems
09151 Immune system
04613 Neutrophil extracellular trap formation
1991 (ELANE)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
1991 (ELANE)
09163 Immune disease
05322 Systemic lupus erythematosus
1991 (ELANE)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:hsa01002]
1991 (ELANE)
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts [BR:hsa03110]
1991 (ELANE)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:hsa04147]
1991 (ELANE)
00536 Glycosaminoglycan binding proteins [BR:hsa00536]
1991 (ELANE)
Enzymes [BR:hsa01000]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.21 Serine endopeptidases
3.4.21.37 leukocyte elastase
1991 (ELANE)
Peptidases and inhibitors [BR:hsa01002]
Serine peptidases
Family S1: chymotrypsin family
1991 (ELANE)
Chaperones and folding catalysts [BR:hsa03110]
Intramolecular chaperones
Other peptidases
1991 (ELANE)
Exosome [BR:hsa04147]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
1991 (ELANE)
Glycosaminoglycan binding proteins [BR:hsa00536]
Heparan sulfate / Heparin
Enzymes
1991 (ELANE)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| Position |
19:852303..856243
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| AA seq |
267 aa
MTLGRRLACLFLACVLPALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGGHFCGATLI
APNFVMSAAHCVANVNVRAVRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVI
LQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSL
CRRSNVCTLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVN
WIDSIIQRSEDNPCPHPRDPDPASRTH |
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| NT seq |
804 nt +upstreamnt +downstreamnt
atgaccctcggccgccgactcgcgtgtcttttcctcgcctgtgtcctgccggccttgctg
ctggggggcaccgcgctggcctcggagattgtggggggccggcgagcgcggccccacgcg
tggcccttcatggtgtccctgcagctgcgcggaggccacttctgcggcgccaccctgatt
gcgcccaacttcgtcatgtcggccgcgcactgcgtggcgaatgtaaacgtccgcgcggtg
cgggtggtcctgggagcccataacctctcgcggcgggagcccacccggcaggtgttcgcc
gtgcagcgcatcttcgaaaacggctacgaccccgtaaacttgctcaacgacatcgtgatt
ctccagctcaacgggtcggccaccatcaacgccaacgtgcaggtggcccagctgccggct
cagggacgccgcctgggcaacggggtgcagtgcctggccatgggctggggccttctgggc
aggaaccgtgggatcgccagcgtcctgcaggagctcaacgtgacggtggtgacgtccctc
tgccgtcgcagcaacgtctgcactctcgtgaggggccggcaggccggcgtctgtttcggg
gactccggcagccccttggtctgcaacgggctaatccacggaattgcctccttcgtccgg
ggaggctgcgcctcagggctctaccccgatgcctttgccccggtggcacagtttgtaaac
tggatcgactctatcatccaacgctccgaggacaacccctgtccccacccccgggacccg
gacccggccagcaggacccactga |
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