KEGG   Rattus norvegicus (rat): 25229
Entry
25229             CDS       T01003                                 
Symbol
Chrm1
Name
(RefSeq) muscarinic acetylcholine receptor M1
  KO
K04129  muscarinic acetylcholine receptor M1
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04020  Calcium signaling pathway
rno04024  cAMP signaling pathway
rno04080  Neuroactive ligand-receptor interaction
rno04082  Neuroactive ligand signaling
rno04151  PI3K-Akt signaling pathway
rno04725  Cholinergic synapse
rno04810  Regulation of actin cytoskeleton
rno05010  Alzheimer disease
rno05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    25229 (Chrm1)
   04151 PI3K-Akt signaling pathway
    25229 (Chrm1)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    25229 (Chrm1)
   04082 Neuroactive ligand signaling
    25229 (Chrm1)
 09150 Organismal Systems
  09156 Nervous system
   04725 Cholinergic synapse
    25229 (Chrm1)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    25229 (Chrm1)
   05022 Pathways of neurodegeneration - multiple diseases
    25229 (Chrm1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:rno04030]
    25229 (Chrm1)
G protein-coupled receptors [BR:rno04030]
 Rhodopsin family
  Biogenic amine
   Acetylcholine (muscarinic)
    25229 (Chrm1)
SSDB
Motif
Pfam: 7tm_1 7TM_GPCR_Srsx 7TM_GPCR_Srbc 7tm_4 7TM_GPCR_Srx Stm1_N
Other DBs
NCBI-GeneID: 25229
NCBI-ProteinID: NP_542951
RGD: 2342
Ensembl: ENSRNOG00000018385
UniProt: P08482 A6HZR8
Position
1:214996180..215012136
AA seq 460 aa
MNTSVPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVN
NYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLIS
FDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYI
QFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSS
SERSQPGAEGSPESPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEV
VIKMPMVDSEAQAPTKQPPKSSPNTVKRPTKKGRDRGGKGQKPRGKEQLAKRKTFSLVKE
KKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTVNPMCYAL
CNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
NT seq 1383 nt   +upstreamnt  +downstreamnt
atgaacacctcagtgccccctgctgtcagtcccaacatcactgtcttggcaccaggaaag
ggtccctggcaggtggccttcatcgggatcaccacaggcctcctgtctctagctacagtg
acaggcaacctactggtactcatctccttcaaggtcaacaccgagctcaagacagtcaac
aactacttcctgctgagcctggcctgtgctgacctcatcattggcaccttctccatgaac
ctctataccacgtacctgctcatgggccactgggctctgggcacactggcctgtgacctc
tggctggccctggactatgtggccagcaacgcctctgtcatgaatcttctgctcatcagc
tttgaccgttacttctcggtgacccgacccctgagctaccgagccaagcgcactccccga
agggcagctctgatgattggcctagcatggctggtttccttcgttctctgggccccagcc
atcctcttctggcaatacctagttggggagcggacagtgctggctgggcagtgctacatc
cagttcctctcccaacccatcatcacttttggcacagccatggccgccttctacctccct
gtcacggtcatgtgtacactgtactggcgcatctaccgggagacagaaaaccgagcccgg
gagctggccgccctgcagggctctgagacaccaggcaaaggtggtggcagcagcagcagc
tcagagaggtcacagccaggggctgaaggctcacccgagtcgcctccaggccgctgctgc
cgctgttgccgggcacccaggctcctgcaggcctacagctggaaggaagaagaagaggag
gatgaaggctccatggagtccctcacatcctccgaaggtgaggagcctggctcagaagtg
gtgatcaagatgcccatggtagattctgaagcacaggcacccaccaagcagcctcccaaa
agctccccaaatacagtcaagaggcccaccaagaaaggccgagaccgaggcggcaagggc
caaaaaccccgagggaaggaacagctggccaagagaaagaccttctcactggtcaaggag
aagaaggcagctcggaccctgagtgccatcctgctggccttcatcctcacctggacacca
tataacatcatggtgctggtatctaccttctgcaaggactgtgttcctgaaaccctgtgg
gagctgggctactggctatgctacgtcaacagcactgtcaaccccatgtgctatgcactg
tgcaacaaagccttccgggacacgttccgcctgctgctgctctgccgctgggacaagagg
cgctggcgcaagatccccaagcgccctggctctgtgcaccgcaccccctcccgccaatgc
taa

  All links  
Gene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (4)   
   RefSeq(nuc) (2)   
   GenBank (1)   
   EMBL (1)   
Protein domain (6)   
   Pfam (6)   
All databases (20)   

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