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3GI2:
Human dihydrofolate reductase Q35K mutant inhibitor complex
PDB ID:
3GI2
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MMDB ID:
77015
PDB Deposition Date:
2009/3/5
Updated in MMDB:
2021/10
Experimental Method:
x-ray diffraction
Resolution:
1.53 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 3GI2: monomeric; determined by author and by software (PISA)
Molecular Components in 3GI2
Label
Count
Molecule
Protein (1 molecule)
A
1
Dihydrofolate Reductase
(Gene symbol:
DHFR
)
Chemicals and Non-standard biopolymers (2 molecules)
1
1
N-({4-[(2-amino-6-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-5-yl)sulfanyl]phenyl}carbonyl)-L-glutamic acid
2
1
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303