2G70: Structure of human PNMT in complex with inhibitor 3-hydroxymethyl-7-nitro-THIQ and AdoMet (SAM)

PDB ID: 2G70Download
MMDB ID: 44439
PDB Deposition Date: 2006/2/27
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.4  Å
Source Organism:
Similar Structures:
Biological Unit for 2G70: monomeric; determined by author and by software (PQS)
Molecular Components in 2G70
Label Count Molecule
Protein (1 molecule)
1
Phenylethanolamine N-methyltransferase
(Gene symbol: PNMT)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
S-ADENOSYLMETHIONINES-ADENOSYLMETHIONINE
2
2
[(3R)-7-NITRO-1,2,3,4-TETRAHYDROISOQUINOLIN-3-YL]METHANOL[(3R)-7-NITRO-1,2,3,4-TETRAHYDROISOQUINOLIN-3-YL]METHANOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303