2UWO: Selective and Dual Action Orally Active Inhibitors of Thrombin and Factor Xa

PDB ID: 2UWODownload
MMDB ID: 46798
PDB Deposition Date: 2007/3/22
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.75  Å
Source Organism:
Similar Structures:
Biological Unit for 2UWO: dimeric; determined by author and by software (PQS)
Molecular Components in 2UWO
Label Count Molecule
Proteins (2 molecules)
1
Coagulation Factor X
(Gene symbol: F10)
Molecule annotation
1
Coagulation Factor X
(Gene symbol: F10)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(2R)-2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}PROPENE-1-SULFONAMIDE(2R)-2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}PROPENE-1-SULFONAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303