2PHB: An Orally Efficacious Factor Xa Inhibitor

PDB ID: 2PHBDownload
MMDB ID: 63230
PDB Deposition Date: 2007/4/10
Updated in MMDB: 2017/10
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 2PHB: dimeric; determined by author and by software (PISA)
Molecular Components in 2PHB
Label Count Molecule
Proteins (2 molecules)
1
Coagulation Factor X, Heavy Chain
(Gene symbol: F10)
Molecule annotation
1
Coagulation Factor X, Light Chain
(Gene symbol: F10)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
Calcium IonCalcium Ion
2
1
(2r,4r)-N~1~-(4-Chlorophenyl)-N~2~-[2-Fluoro-4-(2-Oxopyridin-1(2h)-Yl)phenyl]-4-Methoxypyrrolidine-1,2-Dicarboxamide(2r,4r)-N~1~-(4-Chlorophenyl)-N~2~-[2-Fluoro-4-(2-Oxopyridin-1(2h)-Yl)phenyl]-4-Methoxypyrrolidine-1,2-Dicarboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303