3LY2: Catalytic Domain of Human Phosphodiesterase 4B in Complex with A Coumarin-Based Inhibitor

PDB ID: 3LY2Download
MMDB ID: 81740
PDB Deposition Date: 2010/2/26
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
Similar Structures:
Biological Unit for 3LY2: monomeric; determined by author and by software (PISA)
Molecular Components in 3LY2
Label Count Molecule
Protein (1 molecule)
1
Camp-specific 3',5'-cyclic Phosphodiesterase 4B
(Gene symbol: PDE4B)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
8-(cyclopentyloxy)-4-[(3,5-dichloropyridin-4-yl)amino]-7-methoxy-2H-chromen-2-one8-(cyclopentyloxy)-4-[(3,5-dichloropyridin-4-yl)amino]-7-methoxy-2H-chromen-2-one
2
1
ZINC IONZINC ION
3
1
MAGNESIUM IONMAGNESIUM ION
4
1
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303