3RAE: Quinolone(Levofloxacin)-DNA cleavage complex of type IV topoisomerase from S. pneumoniae

PDB ID: 3RAEDownload
MMDB ID: 98943
PDB Deposition Date: 2011/3/28
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.9  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 3RAE: octameric; determined by author and by software (PISA)
Molecular Components in 3RAE
Label Count Molecule
Proteins (4 molecules)
2
DNA Topoisomerase 4 Subunit a
Molecule annotation
2
DNA Topoisomerase 4 Subunit B
Molecule annotation
Nucleotides(4 molecules)
1
5'-d(*cp*ap*tp*gp*ap*ap*t)-3'
Molecule annotation
1
5'-d(p*ap*gp*tp*cp*ap*tp*tp*cp*ap*tp*g)-3'
Molecule annotation
1
5'-d(*cp*gp*tp*gp*cp*ap*t)-3'
Molecule annotation
1
5'-d(p*gp*ap*cp*tp*ap*tp*gp*cp*ap*cp*g)-3'
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
6
MAGNESIUM IONMAGNESIUM ION
2
2
(3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid(3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303