4HEU: Crystal Structure Of Pde10a With A Biaryl Ether Inhibitor ((1-(3-(4- ((1h-Benzo[d]imidazol-2-Yl)amino)phenoxy)pyridin-2-Yl)piperidin-4- Yl)methanol)

PDB ID: 4HEUDownload
MMDB ID: 105808
PDB Deposition Date: 2012/10/4
Updated in MMDB: 2012/12
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 4HEU: trimeric; determined by software (PISA)
Molecular Components in 4HEU
Label Count Molecule
Proteins (3 molecules)
3
Camp and Camp-inhibited Cgmp 3',5'-cyclic Phosphodiesterase 10A
(Gene symbol: PDE10A)
Molecule annotation
Chemicals and Non-standard biopolymers (30 molecules)
1
6
Zinc IonZinc Ion
2
21
Sulfate IonSulfate Ion
3
3
(1-{3-[4-(1h-Benzimidazol-2-Ylamino)phenoxy]pyridin-2-Yl}piperidin-4-Yl)methanol(1-{3-[4-(1h-Benzimidazol-2-Ylamino)phenoxy]pyridin-2-Yl}piperidin-4-Yl)methanol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303