4NTJ: Structure of the human P2Y12 receptor in complex with an antithrombotic drug

PDB ID: 4NTJDownload
MMDB ID: 118647
PDB Deposition Date: 2013/12/2
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 2.62  Å
Source Organism:
Similar Structures:
Biological Unit for 4NTJ: monomeric; determined by author and by software (PISA)
Molecular Components in 4NTJ
Label Count Molecule
Protein (1 molecule)
1
P2Y Purinoceptor 12,soluble Cytochrome B562,p2y Purinoceptor 12
(Gene symbol: P2RY12)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
ethyl 6-{4-[(benzylsulfonyl)carbamoyl]piperidin-1-yl}-5-cyano-2-methylpyridine-3-carboxylateethyl 6-{4-[(benzylsulfonyl)carbamoyl]piperidin-1-yl}-5-cyano-2-methylpyridine-3-carboxylate
2
2
CHOLESTEROLCHOLESTEROL
3
2
(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303