Abstract
Three new phloroglucinol type compounds Indigoferin-A (1), Indigoferin-B (2) and Indigoferin-C (3), along with a known compound β-sitosterol were isolated from the Indegofera gerardiana Wall. The structures of Indigoferin-A (1), Indigoferin-B (2), and Indigoferin-C (3) were deduced on the basis of spectroscopic techniques (EI-MS, HREI-MS, (1)H NMR, (13)C NMR, HMQC, and HMBC). The urease inhibition studies on all the four compounds have also been carried out.
MeSH terms
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Enzyme Inhibitors / chemistry
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Enzyme Inhibitors / isolation & purification
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Enzyme Inhibitors / pharmacology*
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Glycosides / chemistry
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Glycosides / isolation & purification
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Glycosides / pharmacology*
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Indigofera / chemistry*
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Ketones / chemistry
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Ketones / isolation & purification
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Ketones / pharmacology*
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Mannosides / chemistry
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Mannosides / isolation & purification
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Mannosides / pharmacology*
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Molecular Structure
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Phloroglucinol / analogs & derivatives*
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Phloroglucinol / chemistry
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Phloroglucinol / isolation & purification
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Phloroglucinol / pharmacology
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Plant Extracts / chemistry
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Plant Extracts / isolation & purification
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Plant Extracts / pharmacology
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Stereoisomerism
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Structure-Activity Relationship
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Urease / antagonists & inhibitors*
Substances
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2-(hydroxymethyl)-6-(4-(5-methylhexyl)phenoxy)tetrahydro-2H-pyran-3,4,5-triol
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6-methyl-1-(4-(3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)phenyl)heptan-1-one
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Enzyme Inhibitors
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Glycosides
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Ketones
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Mannosides
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Plant Extracts
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indigoferin-C
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Phloroglucinol
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Urease