4-Chloro-1-hydrazinophthalazine - CAS 51935-42-3
Catalog: |
BB055580 |
Product Name: |
4-Chloro-1-hydrazinophthalazine |
CAS: |
51935-42-3 |
Synonyms: |
1-Chloro-4-hydrazinophthalazine; 1-Chloro-4-hydrazinylphthalazine; 1-Hydrazino-4-chlorophthalazine |
IUPAC Name: | (4-chlorophthalazin-1-yl)hydrazine |
Description: | 4-Chloro-1-hydrazinophthalazine is an intermediate in the synthesis of novel 1,2,4-triazolo[3,4-a]phthalazine derivatives with anticancer activities. |
Molecular Weight: | 194.62 |
Molecular Formula: | C8H7ClN4 |
Canonical SMILES: | C1=CC=C2C(=C1)C(=NN=C2Cl)NN |
InChI: | InChI=1S/C8H7ClN4/c9-7-5-3-1-2-4-6(5)8(11-10)13-12-7/h1-4H,10H2,(H,11,13) |
InChI Key: | UQTJGZYAFKMABR-UHFFFAOYSA-N |
Solubility: | DMSO, Methanol:Water |
Appearance: | Light Yellow Powder |
References: | Hameed, P. S., et al. J. Med. Chem., 57, 5702 (2014). |
GHS Hazard Statement: | H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
CN-110845457-A | Usnic acid derivative, preparation method thereof and application of usnic acid derivative in Alzheimer disease medicine | 20191022 |
WO-2019133666-A1 | Triazolophthalazine compounds, use as anti-human immunodeficiency virus inhibitors of hiv vif-dependent degradation of apobec3 | 20171228 |
US-2019298717-A1 | Hydralazine and Active Derivatives Thereof for Neuronal Cell Survival and Regeneration | 20160314 |
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US-2020165253-A1 | Phthalazine Derivatives, Preparation Method, Pharmaceutical Composition and Usage Thereof | 20151208 |
WO-2017097217-A1 | Phthalazine derivatives, and preparation method, pharmaceutical composition and use thereof | 20151208 |
EP-3025716-A1 | Substance for treatment or relief of pain | 20120214 |
EP-3025716-B1 | Substance for treatment or relief of pain | 20120214 |
JP-2015509935-A | Substances that treat and relieve pain | 20120214 |
JP-6061956-B2 | Substances that treat and relieve pain | 20120214 |
Complexity: | 178 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 194.0359239 |
Formal Charge: | 0 |
Heavy Atom Count: | 13 |
Hydrogen Bond Acceptor Count: | 4 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 194.0359239 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 63.8Ų |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 1.6 |
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