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Found 238 with Last Name = 'abbot' and Initial = 's'
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50111856(CHEMBL21249 | {(R)-2-Amino-4-[benzo[1,3]dioxol-5-y...)
Affinity DataIC50:  0.0240nMAssay Description:Inhibitory activity against Procollagen C-Proteinase (PCP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50111848((R)-2-[Benzo[1,3]dioxol-5-ylmethyl-(4-methoxy-benz...)
Affinity DataIC50:  0.200nMAssay Description:Inhibitory activity against Procollagen C-Proteinase (PCP)More data for this Ligand-Target Pair
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50111848((R)-2-[Benzo[1,3]dioxol-5-ylmethyl-(4-methoxy-benz...)
Affinity DataIC50:  0.200nMAssay Description:Inhibitory activity against Procollagen C-Proteinase (PCP)More data for this Ligand-Target Pair
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50102948(CHEMBL279023 | {(R)-4-[Benzo[1,3]dioxol-5-ylmethyl...)
Affinity DataIC50:  3.90nMAssay Description:Inhibitory activity against Procollagen C-Proteinase (PCP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50111808(CHEMBL282484 | {(R)-2-Amino-4-[benzo[1,3]dioxol-5-...)
Affinity DataIC50:  4.60nMAssay Description:Inhibitory activity against Procollagen C-Proteinase (PCP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50111840((R)-N-Hydroxy-2-[(4-methoxy-benzenesulfonyl)-(2-tr...)
Affinity DataIC50:  6nMAssay Description:Inhibitory activity against Procollagen C-Proteinase (PCP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50102988(CHEMBL21486 | {(R)-4-[Benzo[1,3]dioxol-5-ylmethyl-...)
Affinity DataIC50:  9nMAssay Description:Inhibitory activity against Procollagen C-Proteinase (PCP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50111842((R)-2-[Benzo[1,3]dioxol-5-ylmethyl-(4-methoxy-benz...)
Affinity DataIC50:  10nMAssay Description:Inhibitory activity against procollagen C-proteinase (PCP).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50111854(CHEMBL21237 | {(R)-2-Amino-4-[benzo[1,3]dioxol-5-y...)
Affinity DataIC50:  14nMAssay Description:Inhibitory activity against Procollagen C-Proteinase (PCP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50402842(CHEMBL2208438)
Affinity DataIC50:  14nMAssay Description:Inhibition of human JNK1 alpha1 using GST-tagged ATF2 as substrate and [gamma33P]ATP incubated for 10 mins prior to substrate addition measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50111861(CHEMBL281582 | {(R)-5-[Benzo[1,3]dioxol-5-ylmethyl...)
Affinity DataIC50:  16nMAssay Description:Inhibitory activity against Procollagen C-Proteinase (PCP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50111858(CHEMBL276883 | {(R)-2-Amino-4-[benzo[1,3]dioxol-5-...)
Affinity DataIC50:  18nMAssay Description:Inhibitory activity against Procollagen C-Proteinase (PCP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50402843(CHEMBL2204113)
Affinity DataIC50:  18nMAssay Description:Inhibition of human JNK1 alpha1 using GST-tagged ATF2 as substrate and [gamma33P]ATP incubated for 10 mins prior to substrate addition measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50402836(CHEMBL2204096)
Affinity DataIC50:  23nMAssay Description:Inhibition of human JNK1 alpha1 using GST-tagged ATF2 as substrate and [gamma33P]ATP incubated for 10 mins prior to substrate addition measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50344131(6-(2,4-difluorophenoxy)-N-isopropyl-1H-pyrazolo[3,...)
Affinity DataIC50:  23nMAssay Description:Inhibition of p38alpha assessed as [33P]gamma-ATP incorporation into myelin basic proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50111839(CHEMBL277252 | {(R)-2-Amino-4-[benzo[1,3]dioxol-5-...)
Affinity DataIC50:  23nMAssay Description:Inhibitory activity against Procollagen C-Proteinase (PCP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50111845((R)-2-[Benzo[1,3]dioxol-5-ylmethyl-(4-methoxy-benz...)
Affinity DataIC50:  23nMAssay Description:Inhibitory activity against Procollagen C-Proteinase (PCP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50111857((R)-2-[Benzo[1,3]dioxol-5-ylmethyl-(4-methoxy-benz...)
Affinity DataIC50:  24nMAssay Description:Inhibitory activity against procollagen C-proteinase (PCP).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50102969(CHEMBL21073 | {(R)-4-[Benzo[1,3]dioxol-5-ylmethyl-...)
Affinity DataIC50:  24nMAssay Description:Inhibitory activity against Procollagen C-Proteinase (PCP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50111815(4-{(R)-[Benzo[1,3]dioxol-5-ylmethyl-(4-methoxy-ben...)
Affinity DataIC50:  26nMAssay Description:Inhibitory activity against procollagen C-proteinase (PCP).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50093836(CHEMBL310992 | {(S)-2-[(2S,3S)-2-(3,4-Dibromo-benz...)
Affinity DataIC50:  26nMAssay Description:Inhibitory effect against Procollagen C-terminal proteinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50111867((R)-2-[Benzo[1,3]dioxol-5-ylmethyl-(4-methoxy-benz...)
Affinity DataIC50:  27nMAssay Description:Inhibitory activity against Procollagen C-Proteinase (PCP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50111805((R)-2-[Benzo[1,3]dioxol-5-ylmethyl-(4-methoxy-benz...)
Affinity DataIC50:  28nMAssay Description:Inhibitory activity against procollagen C-proteinase (PCP).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50402843(CHEMBL2204113)
Affinity DataIC50:  28nMAssay Description:Inhibition of human JNK2 alpha2 using GST-tagged ATF2 as substrate and [gamma33P]ATP incubated for 10 mins prior to substrate addition measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50093871((2R,3R)-2-(2,5-Dichloro-benzenesulfonylamino)-3-me...)
Affinity DataIC50:  29nMAssay Description:Inhibitory effect against Procollagen C-terminal proteinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50402840(CHEMBL2204112)
Affinity DataIC50:  30nMAssay Description:Inhibition of human JNK1 alpha1 using GST-tagged ATF2 as substrate and [gamma33P]ATP incubated for 10 mins prior to substrate addition measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50402839(CHEMBL2204109)
Affinity DataIC50:  30nMAssay Description:Inhibition of human JNK1 alpha1 using GST-tagged ATF2 as substrate and [gamma33P]ATP incubated for 10 mins prior to substrate addition measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50111849((R)-2-[(4-Chloro-3-nitro-benzyl)-(4-methoxy-benzen...)
Affinity DataIC50:  30nMAssay Description:Inhibitory activity against Procollagen C-Proteinase (PCP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50093834((2R,3R)-2-(3,4-Dibromo-benzenesulfonylamino)-3-met...)
Affinity DataIC50:  30nMAssay Description:Inhibitory effect against Procollagen C-terminal proteinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50402841(CHEMBL2204108)
Affinity DataIC50:  30nMAssay Description:Inhibition of human JNK1 alpha1 using GST-tagged ATF2 as substrate and [gamma33P]ATP incubated for 10 mins prior to substrate addition measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50402842(CHEMBL2208438)
Affinity DataIC50:  32nMAssay Description:Inhibition of human JNK2 alpha2 using GST-tagged ATF2 as substrate and [gamma33P]ATP incubated for 10 mins prior to substrate addition measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50111841((S)-2-[Benzo[1,3]dioxol-5-ylmethyl-(4-methoxy-benz...)
Affinity DataIC50:  32nMAssay Description:Inhibitory activity against Procollagen C-Proteinase (PCP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50111835((R)-2-[Benzo[1,3]dioxol-5-ylmethyl-(4-methoxy-benz...)
Affinity DataIC50:  32nMAssay Description:Inhibitory activity against Procollagen C-Proteinase (PCP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50093840((2S,3S)-2-(4,5-Dibromo-thiophene-2-sulfonylamino)-...)
Affinity DataIC50:  32nMAssay Description:Inhibitory effect against Procollagen C-terminal proteinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50111824((R)-2-[Benzo[1,3]dioxol-5-ylmethyl-(4-methoxy-benz...)
Affinity DataIC50:  36nMAssay Description:Inhibitory activity against Procollagen C-Proteinase (PCP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50111822((R)-2-[(4-Bromo-benzyl)-(4-methoxy-benzenesulfonyl...)
Affinity DataIC50:  37nMAssay Description:Inhibitory activity against Procollagen C-Proteinase (PCP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50344129(6-(2,4-difluorophenoxy)-N-(1-(methylsulfonyl)piper...)
Affinity DataIC50:  38nMAssay Description:Inhibition of p38alpha assessed as [33P]gamma-ATP incorporation into myelin basic proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50402837(CHEMBL2204107)
Affinity DataIC50:  38nMAssay Description:Inhibition of human JNK1 alpha1 using GST-tagged ATF2 as substrate and [gamma33P]ATP incubated for 10 mins prior to substrate addition measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50111860((R)-N-Hydroxy-2-[(4-methoxy-benzenesulfonyl)-(3-ph...)
Affinity DataIC50:  40nMAssay Description:Inhibitory activity against Procollagen C-Proteinase (PCP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50111843((R)-2-[Benzo[1,3]dioxol-5-ylmethyl-(4-methoxy-benz...)
Affinity DataIC50:  40nMAssay Description:Inhibitory activity against Procollagen C-Proteinase (PCP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50373215(CHEMBL259060)
Affinity DataIC50:  43nMAssay Description:Inhibition of human JNK1 alpha1 using GST-tagged ATF2 as substrate and [gamma33P]ATP incubated for 10 mins prior to substrate addition measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50093876(CHEMBL83127 | {1-[(1S,2R)-1-((S)-1-Hydroxycarbamoy...)
Affinity DataIC50:  43nMAssay Description:Inhibitory effect against Procollagen C-terminal proteinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50093837((2R,3R)-2-(4-Chloro-4,6-dimethyl-cyclohexa-1,5-die...)
Affinity DataIC50:  43nMAssay Description:Inhibitory effect against Procollagen C-terminal proteinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50093869(CHEMBL86076 | {1-[(1S,2R)-1-((S)-1-Hydroxycarbamoy...)
Affinity DataIC50:  44nMAssay Description:Inhibitory effect against Procollagen C-terminal proteinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50402838(CHEMBL2204114)
Affinity DataIC50:  45nMAssay Description:Inhibition of human JNK1 alpha1 using GST-tagged ATF2 as substrate and [gamma33P]ATP incubated for 10 mins prior to substrate addition measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50111859((S)-2-[Benzo[1,3]dioxol-5-ylmethyl-(4-methoxy-benz...)
Affinity DataIC50:  45nMAssay Description:Inhibitory activity against Procollagen C-Proteinase (PCP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50344123((R)-6-(2,4-difluorophenoxy)-N-(1-(methylsulfonyl)p...)
Affinity DataIC50:  45nMAssay Description:Inhibition of p38alpha assessed as [33P]gamma-ATP incorporation into myelin basic proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50402835(CHEMBL2204106)
Affinity DataIC50:  47nMAssay Description:Inhibition of human JNK1 alpha1 using GST-tagged ATF2 as substrate and [gamma33P]ATP incubated for 10 mins prior to substrate addition measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50093872((2R,3R)-3-Methyl-2-(2,4,5-trichloro-benzenesulfony...)
Affinity DataIC50:  49nMAssay Description:Inhibitory effect against Procollagen C-terminal proteinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50402841(CHEMBL2204108)
Affinity DataIC50:  50nMAssay Description:Inhibition of human JNK2 alpha2 using GST-tagged ATF2 as substrate and [gamma33P]ATP incubated for 10 mins prior to substrate addition measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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