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Found 31 with Last Name = 'abrams' and Initial = 'b'
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216194(CHEMBL391935 | N-(2-chlorophenethyl)-N-(pyrrolidin...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216201(CHEMBL233987 | N-(2-methoxyphenethyl)-4-(6-aza-bic...)
Affinity DataIC50:  29nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216180(CHEMBL233799 | N-(2-methoxyphenethyl)-N-(pyrrolidi...)
Affinity DataIC50:  37nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216199(4-(2-aza-bicyclo[2.2.1]heptan-2-ylmethyl)-N-(2-met...)
Affinity DataIC50:  95nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216188(CHEMBL233422 | N-(2-methoxyphenethyl)-4-(((1S,2S)-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216193(CHEMBL233609 | N-(2-methoxyphenethyl)-4-(((S)-2-(m...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216197(CHEMBL233610 | N-(2-methoxyphenethyl)-4-(((S)-2-(m...)
Affinity DataIC50:  160nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216181((R)-N-(2-methoxyphenethyl)-4-((diethylamino)methyl...)
Affinity DataIC50:  170nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216204(CHEMBL394028 | N-(2-methoxyphenethyl)-4-(piperidin...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216206(CHEMBL393989 | N-(2-methoxyphenethyl)-4-(benzyloxy...)
Affinity DataIC50:  310nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216191(CHEMBL232587 | N-(2,6-dichlorophenethyl)-4-((dieth...)
Affinity DataIC50:  430nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216187(CHEMBL232777 | N-(3-chlorophenethyl)-4-(benzyloxy)...)
Affinity DataIC50:  510nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216196(CHEMBL231776 | N-(2-methoxyphenethyl)-4-((diethyla...)
Affinity DataIC50:  540nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216183(CHEMBL233573 | N-(2-chlorophenethyl)-4-(benzyloxy)...)
Affinity DataIC50:  590nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216207(CHEMBL233572 | N-(2-chlorophenethyl)-4-((diethylam...)
Affinity DataIC50:  840nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216208((S)-N-(2-methoxyphenethyl)-4-((diethylamino)methyl...)
Affinity DataIC50:  970nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216186(CHEMBL232577 | N-(2-chlorophenethyl)-4-isopropoxy-...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216203(4-diethylaminomethyl-N-pyrrolidin-3-yl-N-(2-o-toly...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216190(CHEMBL232776 | N-(4-chlorophenethyl)-4-((diethylam...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216205(CHEMBL233574 | N-(2-chlorobenzyl)-4-isopropoxy-N-(...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216184(CHEMBL233165 | N-(2-fluorophenethyl)-4-isopropoxy-...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216189(CHEMBL233166 | N-(3-chlorophenethyl)-4-isopropoxy-...)
Affinity DataIC50:  9.60E+3nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216182(CHEMBL232778 | N-(2-ethoxyphenethyl)-4-((diethylam...)
Affinity DataIC50: >1.60E+4nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216185(CHEMBL397866 | N-(2-chlorophenethyl)-4-isopropoxy-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216198(CHEMBL233419 | N-(2-chlorophenethyl)-4-isopropoxy-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216192(CHEMBL233607 | N-(2-chlorophenethyl)-N-(azetidin-3...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216200(CHEMBL233605 | N-(2-chlorophenethyl)-N-(1-formylpy...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216202(CHEMBL233797 | N-(2-chlorophenethyl)-4-(piperidin-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216195(CHEMBL233606 | N-(2-chlorophenethyl)-4-isopropoxy-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216181((R)-N-(2-methoxyphenethyl)-4-((diethylamino)methyl...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of urokinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216181((R)-N-(2-methoxyphenethyl)-4-((diethylamino)methyl...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed