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Found 38 with Last Name = 'adolfsson' and Initial = 'h'
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50300187(CHEMBL573106 | N-[4-(1-BENZYLCARBAMOYL-2-METHYL-PR...)
Affinity DataKi: <1nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) by resolved fluorescence assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307354(CHEMBL591700 | N-[(1S,2S,4R)-4-((S)-1-Benzylcarbam...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) by resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307360(CHEMBL591699 | N1-((2S,3S,5R)-6-((S)-1-(benzylamin...)
Affinity DataKi:  2.10nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) by resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307353(CHEMBL591491 | N-[(1S,2S,4R)-4-((S)-1-Benzylcarbam...)
Affinity DataKi:  3nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) by resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307361(CHEMBL591644 | N-[(1S,2S,4R)-4-((S)-1-Benzylcarbam...)
Affinity DataKi:  3.10nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) by resolved fluorescence assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307352(CHEMBL591478 | N-[(1S,2S,4R)-4-((S)-1-Benzylcarbam...)
Affinity DataKi:  3.30nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) by resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307359(CHEMBL591371 | N1-((2S,3S,5R)-6-((S)-1-(benzylamin...)
Affinity DataKi:  20nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) by resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307353(CHEMBL591491 | N-[(1S,2S,4R)-4-((S)-1-Benzylcarbam...)
Affinity DataKi:  61nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307359(CHEMBL591371 | N1-((2S,3S,5R)-6-((S)-1-(benzylamin...)
Affinity DataKi:  62nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307357(CHEMBL601523 | N-[(1S,2S,4R)-2-Azido-4-((S)-1-benz...)
Affinity DataKi:  70nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) by resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307355(CHEMBL601521 | N-[(1S,4R)-4-((S)-1-Benzylcarbamoyl...)
Affinity DataKi:  130nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) by resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307352(CHEMBL591478 | N-[(1S,2S,4R)-4-((S)-1-Benzylcarbam...)
Affinity DataKi:  130nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307358(CHEMBL591701 | N-[(1S,2S,4R)-4-((S)-1-Benzylcarbam...)
Affinity DataKi:  140nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) by resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307356(CHEMBL601522 | N-[(1S,2R,4R)-4-((S)-1-Benzylcarbam...)
Affinity DataKi:  210nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) by resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307361(CHEMBL591644 | N-[(1S,2S,4R)-4-((S)-1-Benzylcarbam...)
Affinity DataKi:  240nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50300187(CHEMBL573106 | N-[4-(1-BENZYLCARBAMOYL-2-METHYL-PR...)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307360(CHEMBL591699 | N1-((2S,3S,5R)-6-((S)-1-(benzylamin...)
Affinity DataKi:  3.35E+3nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307358(CHEMBL591701 | N-[(1S,2S,4R)-4-((S)-1-Benzylcarbam...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307357(CHEMBL601523 | N-[(1S,2S,4R)-2-Azido-4-((S)-1-benz...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307356(CHEMBL601522 | N-[(1S,2R,4R)-4-((S)-1-Benzylcarbam...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307355(CHEMBL601521 | N-[(1S,4R)-4-((S)-1-Benzylcarbamoyl...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50300187(CHEMBL573106 | N-[4-(1-BENZYLCARBAMOYL-2-METHYL-PR...)
Affinity DataIC50:  0.320nMAssay Description:Inhibition of human brain BACE1 expressed in Escherichia coli BL21(DE) by TRF assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50300171(CHEMBL572692 | N-[(1S,2S,4R)-1-(3,5-difluoro-pheno...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human brain BACE1 expressed in Escherichia coli BL21(DE) by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50300172(CHEMBL572773 | N-[(1S,2S,4R)-5-benzyloxy-1-(3,5-di...)
Affinity DataIC50:  240nMAssay Description:Inhibition of human brain BACE1 expressed in Escherichia coli BL21(DE) by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50300173(CHEMBL572772 | N-[(1S,2S,4R)-1-(3,5-difluoro-pheno...)
Affinity DataIC50:  480nMAssay Description:Inhibition of human brain BACE1 expressed in Escherichia coli BL21(DE) by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50300176(2-Ethyl-6-methyl-7,7-dioxo-6,7,8,9-tetrahydro-7lam...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human brain BACE1 expressed in Escherichia coli BL21(DE) by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50300174(CHEMBL583699 | N-[1S-(3,5-difluoro-phenoxymethyl)-...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human brain BACE1 expressed in Escherichia coli BL21(DE) by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50300175(CHEMBL583703 | N-[(1S,2S,4R)-1-(3,5-difluoro-pheno...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human brain BACE1 expressed in Escherichia coli BL21(DE) by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50300177(CHEMBL583303 | N-[1S-(3,5-difluoro-phenoxymethyl)-...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of human brain BACE1 expressed in Escherichia coli BL21(DE) by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50300178(CHEMBL583697 | N-[(1S,2S,4R)-5-cyclopropylmethoxy-...)
Affinity DataIC50:  1.86E+3nMAssay Description:Inhibition of human brain BACE1 expressed in Escherichia coli BL21(DE) by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50300179(CHEMBL583700 | N-[(1S,2S,4R)-5-allyloxy-1-(3,5-dif...)
Affinity DataIC50:  2.02E+3nMAssay Description:Inhibition of human brain BACE1 expressed in Escherichia coli BL21(DE) by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50300180(CHEMBL573378 | N-[(1S,2S,4R)-1-(3,5-difluoro-pheno...)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of human brain BACE1 expressed in Escherichia coli BL21(DE) by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50300184(CHEMBL583702 | N-[(1S,2S,4R)-1-(3,5-difluoro-pheno...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human brain BACE1 expressed in Escherichia coli BL21(DE) by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50300181(CHEMBL583496 | N-[(1S,2S,4R)-1-(3,5-difluoro-pheno...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human brain BACE1 expressed in Escherichia coli BL21(DE) by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50300183(CHEMBL583701 | N-[(1S,2S,4R)-1-(3,5-difluoro-pheno...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human brain BACE1 expressed in Escherichia coli BL21(DE) by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50300182(CHEMBL572771 | N-[(1S,2S,4R)-1-(3,5-difluoro-pheno...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human brain BACE1 expressed in Escherichia coli BL21(DE) by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50300186(CHEMBL583302 | N-[5-benzylamino-1S-(3,5-difluoro-p...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human brain BACE1 expressed in Escherichia coli BL21(DE) by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50300185(CHEMBL583915 | N-[5-benzylamino-1S-(3,5-difluoro-p...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human brain BACE1 expressed in Escherichia coli BL21(DE) by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed