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Found 62 with Last Name = 'adornato' and Initial = 'i'
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506669(CHEMBL4459307)
Affinity DataKi:  6.20nMAssay Description:Uncompetitive inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21(DE3)pLysS assessed as dissociation constant of enzy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506667(CHEMBL4448571)
Affinity DataKi:  16nMAssay Description:Uncompetitive inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21(DE3)pLysS assessed as dissociation constant of enzy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506669(CHEMBL4459307)
Affinity DataKi: >300nMAssay Description:Uncompetitive inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21(DE3)pLysS assessed as dissociation constant of enzy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506667(CHEMBL4448571)
Affinity DataKi: >500nMAssay Description:Uncompetitive inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21(DE3)pLysS assessed as dissociation constant of enzy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50232100(CHEMBL4061225)
Affinity DataKi:  1.00E+3nMAssay Description:Mixed non-competitive inhibition of full length recombinant human PTP1B assessed as enzyme-substrate-inhibitor complex using pNPP as substrate by dou...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50232102(CHEMBL4080177)
Affinity DataKi:  1.40E+3nMAssay Description:Competitive inhibition of full length recombinant human PTP1B assessed as enzyme-inhibitor complex using pNPP as substrate by double reciprocal plot ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50232101(CHEMBL4098207)
Affinity DataKi:  1.50E+3nMAssay Description:Mixed non-competitive inhibition of full length recombinant human PTP1B assessed as enzyme-substrate-inhibitor complex using pNPP as substrate by dou...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50232103(CHEMBL4089378)
Affinity DataKi:  2.30E+3nMAssay Description:Mixed non-competitive inhibition of full length recombinant human PTP1B assessed as enzyme-substrate-inhibitor complex using pNPP as substrate by dou...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50232093(CHEMBL4072175)
Affinity DataKi:  4.40E+3nMAssay Description:Competitive inhibition of full length recombinant human PTP1B assessed as enzyme-inhibitor complex using pNPP as substrate by double reciprocal plot ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506663(CHEMBL4483785)
Affinity DataKi:  7.60E+3nMAssay Description:Mixed non-competitive inhibition of human full-length GST-fused PTP1B expressed in bacterial expression system assessed as assessed as dissociation c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50232094(CHEMBL4062661)
Affinity DataKi:  9.90E+3nMAssay Description:Competitive inhibition of full length recombinant human PTP1B assessed as enzyme-inhibitor complex using pNPP as substrate by double reciprocal plot ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506669(CHEMBL4459307)
Affinity DataKi:  1.20E+4nMAssay Description:Non-competitive inhibition of human full-length GST-fused PTP1B expressed in bacterial expression system assessed as dissociation constant of enzyme-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506669(CHEMBL4459307)
Affinity DataKi:  1.20E+4nMAssay Description:Non-competitive inhibition of human full-length GST-fused PTP1B expressed in bacterial expression system assessed as dissociation constant of enzyme-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506667(CHEMBL4448571)
Affinity DataKi:  1.31E+4nMAssay Description:Non-competitive inhibition of human full-length GST-fused PTP1B expressed in bacterial expression system assessed as dissociation constant of enzyme-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506667(CHEMBL4448571)
Affinity DataKi:  1.31E+4nMAssay Description:Non-competitive inhibition of human full-length GST-fused PTP1B expressed in bacterial expression system assessed as dissociation constant of enzyme-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506663(CHEMBL4483785)
Affinity DataKi:  4.06E+4nMAssay Description:Mixed non-competitive inhibition of human full-length GST-fused PTP1B expressed in bacterial expression system assessed as assessed as dissociation c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50334180(2-(4-oxo-5-(3-phenoxybenzylidene)-2-thioxothiazoli...)
Affinity DataIC50:  25nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506665(CHEMBL4554837)
Affinity DataIC50:  40nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50149769((Z)-2-(5-(4-(benzyloxy)benzylidene)-4-oxo-2-thioxo...)
Affinity DataIC50:  52nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50149743((Z)-2-(5-(3-(benzyloxy)benzylidene)-4-oxo-2-thioxo...)
Affinity DataIC50:  53nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506669(CHEMBL4459307)
Affinity DataIC50:  56nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50334181(2-(4-oxo-5-(4-phenoxybenzylidene)-2-thioxothiazoli...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50016233(CHEMBL3262475)
Affinity DataIC50:  64nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50334182(2-(5-(3-methoxybenzylidene)-4-oxo-2-thioxothiazoli...)
Affinity DataIC50:  78nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50049730(2-(5-(2-methyl-3-phenylallylidene)-4-oxo-2-thioxot...)
Affinity DataIC50:  102nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506664(CHEMBL4436037)
Affinity DataIC50:  104nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506668(CHEMBL1384494)
Affinity DataIC50:  125nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50016231(CHEMBL3262477)
Affinity DataIC50:  139nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50016232(CHEMBL3262476)
Affinity DataIC50:  194nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50016230(CHEMBL3262478)
Affinity DataIC50:  228nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506667(CHEMBL4448571)
Affinity DataIC50:  276nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506666(CHEMBL4455326)
Affinity DataIC50:  323nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506662(CHEMBL4483615)
Affinity DataIC50:  364nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50284960(CHEMBL50626 | H3VO4 | Vanadiumsaeure | [VO(OH)3] |...)
Affinity DataIC50:  400nMAssay Description:Inhibition of human full-length GST-fused PTP1B expressed in bacterial expression system using pNPP as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506663(CHEMBL4483785)
Affinity DataIC50:  1.41E+3nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50232100(CHEMBL4061225)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of full length recombinant human PTP1B using pNPP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50232095(CHEMBL4081501)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of full length recombinant human PTP1B using pNPP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50232102(CHEMBL4080177)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of full length recombinant human PTP1B using pNPP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50232096(CHEMBL4099520)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of full length recombinant human PTP1B using pNPP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50232101(CHEMBL4098207)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of full length recombinant human PTP1B using pNPP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50232097(CHEMBL4091784)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of full length recombinant human PTP1B using pNPP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50232094(CHEMBL4062661)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of full length recombinant human PTP1B using pNPP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50232104(CHEMBL4070916)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibition of full length recombinant human PTP1B using pNPP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50232098(CHEMBL4097088)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of full length recombinant human PTP1B using pNPP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50232093(CHEMBL4072175)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of full length recombinant human PTP1B using pNPP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50232099(CHEMBL4069888)
Affinity DataIC50:  1.06E+4nMAssay Description:Inhibition of full length recombinant human PTP1B using pNPP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506663(CHEMBL4483785)
Affinity DataIC50:  1.06E+4nMAssay Description:Inhibition of human full-length GST-fused PTP1B expressed in bacterial expression system using pNPP as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506667(CHEMBL4448571)
Affinity DataIC50:  1.24E+4nMAssay Description:Inhibition of human full-length GST-fused PTP1B expressed in bacterial expression system using pNPP as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50232103(CHEMBL4089378)
Affinity DataIC50:  1.45E+4nMAssay Description:Inhibition of full length recombinant human PTP1B using pNPP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506669(CHEMBL4459307)
Affinity DataIC50:  3.25E+4nMAssay Description:Inhibition of human full-length GST-fused PTP1B expressed in bacterial expression system using pNPP as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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