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Found 36 with Last Name = 'ahmed' and Initial = 'sz'
TargetType-1 angiotensin II receptor B(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50004154(2-Butyl-4-chloro-6-methyl-1-[2'-(1H-tetrazol-5-yl)...)
Affinity DataKi:  1nMAssay Description:Inhibition of [125I]- Sar,Ile8-angiotensin II binding to rat adrenal corticcal membrane angiotensin II receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50004155(2-Butyl-6-chloro-4,4-dimethyl-1-[2'-(1H-tetrazol-5...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of [125I]- Sar,Ile8-angiotensin II binding to rat adrenal corticcal membrane angiotensin II receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50004164(2-Butyl-4-chloro-6-methyl-1-[2'-(1H-tetrazol-5-yl)...)
Affinity DataKi:  8.30nMAssay Description:Inhibition of [125I]- Sar,Ile8-angiotensin II binding to rat adrenal corticcal membrane angiotensin II receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50406795(Cozaar | LOSARTAN POTASSIUM)
Affinity DataKi:  9nMAssay Description:In vitro antagonistic potency against angiotensin II receptor using [125I]- Sar,Ile8-angiotensin II as the radioligand in rat adrenal cortical membra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50004153(2-Butyl-1-(2'-carboxy-biphenyl-4-ylmethyl)-4-chlor...)
Affinity DataKi:  41nMAssay Description:Inhibition of [125I]- Sar,Ile8-angiotensin II binding to rat adrenal corticcal membrane angiotensin II receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281270(Acetic acid (2S,3S)-5-(2-dimethylamino-ethyl)-8-me...)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]-diltiazem from L-type calcium channel of guinea pig striated muscleMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor B(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50004160(CHEMBL145036 | Sodium; 4'-(2-butyl-6-chloro-5-etho...)
Affinity DataKi:  58nMAssay Description:Inhibition of [125I]- Sar,Ile8-angiotensin II binding to rat adrenal corticcal membrane angiotensin II receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50004163(CHEMBL342287 | Sodium; 4'-(2-butyl-5-ethoxycarbony...)
Affinity DataKi:  82nMAssay Description:Inhibition of [125I]- Sar,Ile8-angiotensin II binding to rat adrenal corticcal membrane angiotensin II receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281272((2R,3S)-5-(2-Dimethylamino-ethyl)-8-methoxy-2-(4-m...)
Affinity DataKi:  85nMAssay Description:Displacement of [3H]-diltiazem from L-type calcium channel of guinea pig striated muscleMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor B(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM82258(CAS_114798-26-4 | Losartan | NSC_3961)
Affinity DataKi:  95nMAssay Description:In vitro antagonistic potency against angiotensin II receptor using [125I]- Sar,Ile8-angiotensin II as the radioligand in rat adrenal cortical membra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50004162(CHEMBL145276 | Sodium; 4'-(2-butyl-5-ethoxycarbony...)
Affinity DataKi:  150nMAssay Description:Inhibition of [125I]- Sar,Ile8-angiotensin II binding to rat adrenal corticcal membrane angiotensin II receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50004156(2-Butyl-1-(2'-carboxy-biphenyl-4-ylmethyl)-4-(4-ch...)
Affinity DataKi:  190nMAssay Description:Inhibition of [125I]- Sar,Ile8-angiotensin II binding to rat adrenal corticcal membrane angiotensin II receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50004704((+)-cis-Diltiazem | (2S,3S)-5-(2-(dimethylamino)et...)
Affinity DataKi:  380nMAssay Description:Displacement of [3H]-diltiazem from L-type calcium channel of guinea pig striated muscleMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281271((2R,3S)-5-(2-Dimethylamino-ethyl)-2-(4-methoxy-phe...)
Affinity DataKi:  540nMAssay Description:Displacement of [3H]-diltiazem from L-type calcium channel of guinea pig striated muscleMore data for this Ligand-Target Pair
In DepthDetails Article
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50000383((3R,4R)-1-(2-Dimethylamino-ethyl)-4-(4-methoxy-phe...)
Affinity DataKi:  650nMAssay Description:Displacement of [3H]-diltiazem from L-type calcium channel of guinea pig striated muscleMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor B(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50004157(2-Butyl-1-(2'-carboxy-biphenyl-4-ylmethyl)-6-methy...)
Affinity DataKi:  850nMAssay Description:Inhibition of [125I]- Sar,Ile8-angiotensin II binding to rat adrenal corticcal membrane angiotensin II receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50004158(2-Butyl-1-(2'-carboxy-biphenyl-4-ylmethyl)-4,6-dim...)
Affinity DataKi:  990nMAssay Description:Inhibition of [125I]- Sar,Ile8-angiotensin II binding to rat adrenal corticcal membrane angiotensin II receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50004159(CHEMBL343622 | Sodium; 4'-(2-butyl-4-chloro-5-etho...)
Affinity DataKi:  1.43E+3nMAssay Description:Inhibition of [125I]- Sar,Ile8-angiotensin II binding to rat adrenal corticcal membrane angiotensin II receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor B(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50004165(CHEMBL144952 | Sodium; 4'-(2-butyl-5-ethoxycarbony...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of [125I]- Sar,Ile8-angiotensin II binding to rat adrenal corticcal membrane angiotensin II receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM5668(2-amino-5-thio-substituted thiazole 45 | BMS-38703...)
Affinity DataIC50:  3nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM5924(BMS-387032 analog 14 | N-(5-{[(5-tert-butyl-1,3-ox...)
Affinity DataIC50:  3nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM5660(2-amino-5-thio-substituted thiazole 25 | 2-aminoth...)
Affinity DataIC50:  5nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM5930(BMS-387032 analog 20 | N-(5-{[(5-tert-butyl-1,3-ox...)
Affinity DataIC50:  11nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM5934(BMS-387032 analog 24 | N-(5-{[(5-tert-butyl-1,3-ox...)
Affinity DataIC50:  18nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM5923(3-amino-N-(5-{[(5-tert-butyl-1,3-oxazol-2-yl)methy...)
Affinity DataIC50:  21nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM5936(4-amino-N-(5-{[(5-tert-butyl-1,3-oxazol-2-yl)methy...)
Affinity DataIC50:  22nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM5683(2-amino-5-thio-substituted thiazole 31 | BMS-38703...)
Affinity DataIC50:  26nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM5932(1-Methyl-N-[5-[[[5-(1,1-dimethylethyl)-2-oxazolyl]...)
Affinity DataIC50:  43nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM5931(BMS-387072 | CHEMBL296468 | N-(5-{[(5-tert-butyl-1...)
Affinity DataIC50:  48nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM5926(BMS-387032 analog 16 | N-(5-{[(5-tert-butyl-1,3-ox...)
Affinity DataIC50:  50nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM5928((+/-)-N-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]met...)
Affinity DataIC50:  50nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM5933(BMS-387032 analog 23 | N-(5-{[(5-tert-butyl-1,3-ox...)
Affinity DataIC50:  74nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM5929((+/-)-N-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]met...)
Affinity DataIC50:  83nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM5937(4-amino-N-(5-{[(5-tert-butyl-1,3-oxazol-2-yl)methy...)
Affinity DataIC50:  150nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM5935(BMS-387032 analog 25 | N-[5-[[[5-(1,1-Dimethylethy...)
Affinity DataIC50:  160nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM5927(BMS-387032 analog 17 | N-(5-{[(5-tert-butyl-1,3-ox...)
Affinity DataIC50:  300nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed