TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
University Of Tennessee
Curated by ChEMBL
University Of Tennessee
Curated by ChEMBL
Affinity DataKi: 2.20E+4nMAssay Description:Inhibition of AICAR transformylase (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 3.40E+4nMAssay Description:Inhibition of human DHFR in presence of DHF and NADPH by UV-vis spectrometry by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 4.80E+4nMAssay Description:Inhibition of human DHFR in presence of DHF and NADPH by UV-vis spectrometry by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 7.20E+4nMAssay Description:Inhibition of human DHFR in presence of DHF and NADPH by UV-vis spectrometry by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+5nMAssay Description:Inhibition of human DHFR in presence of DHF and NADPH by UV-vis spectrometry by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.60E+5nMAssay Description:Inhibition of human DHFR in presence of DHF and NADPH by UV-vis spectrometry by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.80E+5nMAssay Description:Inhibition of human DHFR in presence of DHF and NADPH by UV-vis spectrometry by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.80E+5nMAssay Description:Inhibition of human DHFR in presence of DHF and NADPH by UV-vis spectrometry by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.60E+5nMAssay Description:Inhibition of human DHFR in presence of DHF and NADPH by UV-vis spectrometry by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 5.60E+5nMAssay Description:Inhibition of human DHFR in presence of DHF and NADPH by UV-vis spectrometry by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 8.10E+5nMAssay Description:Inhibition of human DHFR in presence of DHF and NADPH by UV-vis spectrometry by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 8.80E+5nMAssay Description:Inhibition of human DHFR in presence of DHF and NADPH by UV-vis spectrometry by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.80E+6nMAssay Description:Inhibition of human DHFR in presence of DHF and NADPH by UV-vis spectrometry by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.80E+6nMAssay Description:Inhibition of human DHFR in presence of DHF and NADPH by UV-vis spectrometry by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.40E+6nMAssay Description:Inhibition of human DHFR in presence of DHF and NADPH by UV-vis spectrometry by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 7.00E+6nMAssay Description:Inhibition of human DHFR in presence of DHF and NADPH by UV-vis spectrometry by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.70E+7nMAssay Description:Inhibition of human DHFR in presence of DHF and NADPH by UV-vis spectrometry by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.80E+7nMAssay Description:Inhibition of human DHFR in presence of DHF and NADPH by UV-vis spectrometry by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Glucagon receptor binding measured as 50% inhibitory concentrationMore data for this Ligand-Target Pair
Affinity DataIC50: 0.240nMAssay Description:Glucagon receptor binding measured as 50% inhibitory concentrationMore data for this Ligand-Target Pair
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
University Of Texas At Dallas
Curated by ChEMBL
University Of Texas At Dallas
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:In vitro receptor binding affinity (95% CL) using rat liver plasma membrane bioassayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Glucagon receptor binding measured as 50% inhibitory concentrationMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Binding affinity towards Glucagon receptor in rat liver plasma membranes by displacement of 125 I-labelled glucagonMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:inhibition of [125]glucagon specific binding.More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Glucagon receptor binding measured as 50% inhibitory concentrationMore data for this Ligand-Target Pair
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
University Of Texas At Dallas
Curated by ChEMBL
University Of Texas At Dallas
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
University Of Texas At Dallas
Curated by ChEMBL
University Of Texas At Dallas
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
University Of Texas At Dallas
Curated by ChEMBL
University Of Texas At Dallas
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
University Of Texas At Dallas
Curated by ChEMBL
University Of Texas At Dallas
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
University Of Texas At Dallas
Curated by ChEMBL
University Of Texas At Dallas
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
University Of Texas At Dallas
Curated by ChEMBL
University Of Texas At Dallas
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Glucagon receptor binding measured as 50% inhibitory concentrationMore data for this Ligand-Target Pair
Affinity DataIC50: 3.75nMAssay Description:Compound was evaluated for its ability to displace radiolabelled glucagonMore data for this Ligand-Target Pair
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
University Of Texas At Dallas
Curated by ChEMBL
University Of Texas At Dallas
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
University Of Texas At Dallas
Curated by ChEMBL
University Of Texas At Dallas
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.60nMAssay Description:Glucagon receptor binding measured as 50% inhibitory concentrationMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Glucagon receptor binding measured as 50% inhibitory concentrationMore data for this Ligand-Target Pair
Affinity DataIC50: 6.40nMAssay Description:Glucagon receptor binding measured as 50% inhibitory concentrationMore data for this Ligand-Target Pair
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
University Of Texas At Dallas
Curated by ChEMBL
University Of Texas At Dallas
Curated by ChEMBL
Affinity DataIC50: 6.60nMAssay Description:Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
University Of Texas At Dallas
Curated by ChEMBL
University Of Texas At Dallas
Curated by ChEMBL
Affinity DataIC50: 6.60nMAssay Description:Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Glucagon receptor binding measured as 50% inhibitory concentrationMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Glucagon receptor binding measured as 50% inhibitory concentrationMore data for this Ligand-Target Pair
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
University Of Texas At Dallas
Curated by ChEMBL
University Of Texas At Dallas
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Compound was evaluated for its ability to displace radiolabelled glucagon (inactive up to 100 microM)More data for this Ligand-Target Pair
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
University Of Texas At Dallas
Curated by ChEMBL
University Of Texas At Dallas
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
University Of Texas At Dallas
Curated by ChEMBL
University Of Texas At Dallas
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Binding affinity towards Glucagon receptor in rat liver plasma membranes by displacement of 125 I-labelled glucagonMore data for this Ligand-Target Pair
Affinity DataIC50: 21.2nMAssay Description:IC50 value of the compound was expressed as inhibition of [125]glucagon specific binding.More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:IC50 value of the compound was expressed as inhibition of [125]glucagon specific binding.More data for this Ligand-Target Pair