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Found 48 with Last Name = 'akhtar' and Initial = 'n'
TargetEstrogen receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM50125052(CHEMBL3623004 | US10130617, Example 1 | WO-2014/19...)
Affinity DataIC50:  140nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM292004((E)-3-(3,5-difluoro-4-(2-((S)-3-fluoro-2-methylpro...)
Affinity DataIC50:  200nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Putra Malaysia

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  250nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate after 10 mins by Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM289785((E)-3-(3,5-Difluoro-4-((1R,3R)-2-((S)-3-fluoro-2-m...)
Affinity DataIC50:  400nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM292005((E)-3-(3,5-difluoro-4-(2-(2-fluoro-2-methylpropyl)...)
Affinity DataIC50:  440nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM292004((E)-3-(3,5-difluoro-4-(2-((S)-3-fluoro-2-methylpro...)
Affinity DataIC50:  570nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Putra Malaysia

Curated by ChEMBL
LigandPNGBDBM50259930(6-(10'Z-heptadecenyl)-salicylicacid | 6-[10'(Z)-he...)
Affinity DataIC50:  573nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate after 10 mins by Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM50125052(CHEMBL3623004 | US10130617, Example 1 | WO-2014/19...)
Affinity DataIC50: <640nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM50125054(CHEMBL3623003 | US10130617, Example 2 | WO-2014/19...)
Affinity DataIC50:  850nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM292003((E)-3-(4-((1R,3R)-2-((S)-3-fluoro-2-methylpropyl)-...)
Affinity DataIC50:  990nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM289785((E)-3-(3,5-Difluoro-4-((1R,3R)-2-((S)-3-fluoro-2-m...)
Affinity DataIC50:  1.00E+3nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM50125054(CHEMBL3623003 | US10130617, Example 2 | WO-2014/19...)
Affinity DataIC50:  1.00E+3nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM299742((E)-3-(3-fluoro-4-(2-((S)-3-fluoro-2-methylpropyl)...)
Affinity DataIC50: <1.20E+3nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM292005((E)-3-(3,5-difluoro-4-(2-(2-fluoro-2-methylpropyl)...)
Affinity DataIC50: <1.30E+3nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM299742((E)-3-(3-fluoro-4-(2-((S)-3-fluoro-2-methylpropyl)...)
Affinity DataIC50:  1.50E+3nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM292003((E)-3-(4-((1R,3R)-2-((S)-3-fluoro-2-methylpropyl)-...)
Affinity DataIC50:  1.60E+3nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM298313((E)-3-(4-(2-((S)-3-fluoro-2-methylpropyl)-3,3-dime...)
Affinity DataIC50:  1.70E+3nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Putra Malaysia

Curated by ChEMBL
LigandPNGBDBM50292424(Anacardic acid 10'Z-monoene | CHEMBL470264)
Affinity DataIC50:  2.17E+3nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate after 10 mins by Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM298314((E)-3-(4-(2-(2-fluoro-2-methylpropyl)-3,3-dimethyl...)
Affinity DataIC50:  2.20E+3nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM298314((E)-3-(4-(2-(2-fluoro-2-methylpropyl)-3,3-dimethyl...)
Affinity DataIC50:  3.00E+3nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Putra Malaysia

Curated by ChEMBL
LigandPNGBDBM50347127(CHEMBL1797234)
Affinity DataIC50:  3.18E+3nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate after 10 mins by Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM298313((E)-3-(4-(2-((S)-3-fluoro-2-methylpropyl)-3,3-dime...)
Affinity DataIC50:  5.00E+3nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
The Islamia University Of Bahawalpur

Curated by ChEMBL
LigandPNGBDBM50106912(CHEMBL3601761)
Affinity DataIC50:  8.53E+3nMAssay Description:Inhibition of jack bean Urease assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
The Islamia University Of Bahawalpur

Curated by ChEMBL
LigandPNGBDBM50106914(CHEMBL3601759)
Affinity DataIC50:  8.93E+3nMAssay Description:Inhibition of jack bean Urease assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
The Islamia University Of Bahawalpur

Curated by ChEMBL
LigandPNGBDBM50106916(CHEMBL3601757)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of jack bean Urease assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Putra Malaysia

Curated by ChEMBL
LigandPNGBDBM50259927(3-[10'(Z)-heptadecenyl]phenol | CHEMBL470127)
Affinity DataIC50:  1.31E+4nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate after 10 mins by Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
The Islamia University Of Bahawalpur

Curated by ChEMBL
LigandPNGBDBM50106878(CHEMBL3601773)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of jack bean Urease assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Putra Malaysia

Curated by ChEMBL
LigandPNGBDBM50347129(CHEMBL1797236)
Affinity DataIC50:  1.72E+4nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate after 10 mins by Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
The Islamia University Of Bahawalpur

Curated by ChEMBL
LigandPNGBDBM50106911(CHEMBL3601762)
Affinity DataIC50:  1.89E+4nMAssay Description:Inhibition of jack bean Urease assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
The Islamia University Of Bahawalpur

Curated by ChEMBL
LigandPNGBDBM50106879(CHEMBL3601772)
Affinity DataIC50:  1.97E+4nMAssay Description:Inhibition of jack bean Urease assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
The Islamia University Of Bahawalpur

Curated by ChEMBL
LigandPNGBDBM50229993(2-thiourea | CHEMBL260876 | Thiocarbamid | Thiohar...)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of jack bean Urease assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
The Islamia University Of Bahawalpur

Curated by ChEMBL
LigandPNGBDBM50106915(CHEMBL3601758)
Affinity DataIC50:  2.18E+4nMAssay Description:Inhibition of jack bean Urease assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
The Islamia University Of Bahawalpur

Curated by ChEMBL
LigandPNGBDBM50106906(CHEMBL3601767)
Affinity DataIC50:  2.46E+4nMAssay Description:Inhibition of jack bean Urease assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
The Islamia University Of Bahawalpur

Curated by ChEMBL
LigandPNGBDBM50106917(CHEMBL3601756)
Affinity DataIC50:  2.58E+4nMAssay Description:Inhibition of jack bean Urease assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
The Islamia University Of Bahawalpur

Curated by ChEMBL
LigandPNGBDBM50106909(CHEMBL3601764)
Affinity DataIC50:  2.67E+4nMAssay Description:Inhibition of jack bean Urease assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
The Islamia University Of Bahawalpur

Curated by ChEMBL
LigandPNGBDBM50106904(CHEMBL3601769)
Affinity DataIC50:  2.87E+4nMAssay Description:Inhibition of jack bean Urease assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
The Islamia University Of Bahawalpur

Curated by ChEMBL
LigandPNGBDBM50106913(CHEMBL3601760)
Affinity DataIC50:  3.23E+4nMAssay Description:Inhibition of jack bean Urease assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
The Islamia University Of Bahawalpur

Curated by ChEMBL
LigandPNGBDBM50106910(CHEMBL3601763)
Affinity DataIC50:  3.98E+4nMAssay Description:Inhibition of jack bean Urease assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
The Islamia University Of Bahawalpur

Curated by ChEMBL
LigandPNGBDBM50106880(CHEMBL3601771)
Affinity DataIC50:  4.13E+4nMAssay Description:Inhibition of jack bean Urease assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
The Islamia University Of Bahawalpur

Curated by ChEMBL
LigandPNGBDBM50106908(CHEMBL3601765)
Affinity DataIC50:  5.26E+4nMAssay Description:Inhibition of jack bean Urease assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
The Islamia University Of Bahawalpur

Curated by ChEMBL
LigandPNGBDBM50106907(CHEMBL3601766)
Affinity DataIC50:  6.53E+4nMAssay Description:Inhibition of jack bean Urease assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
The Islamia University Of Bahawalpur

Curated by ChEMBL
LigandPNGBDBM50106918(CHEMBL3601372)
Affinity DataIC50:  8.83E+4nMAssay Description:Inhibition of jack bean Urease assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
The Islamia University Of Bahawalpur

Curated by ChEMBL
LigandPNGBDBM50106881(CHEMBL3601770)
Affinity DataIC50:  8.92E+4nMAssay Description:Inhibition of jack bean Urease assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
The Islamia University Of Bahawalpur

Curated by ChEMBL
LigandPNGBDBM50106905(CHEMBL3601768)
Affinity DataIC50:  1.36E+5nMAssay Description:Inhibition of jack bean Urease assessed as ammonia production after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Putra Malaysia

Curated by ChEMBL
LigandPNGBDBM50347130(CHEMBL1797237)
Affinity DataIC50:  1.78E+5nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate after 10 mins by Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Putra Malaysia

Curated by ChEMBL
LigandPNGBDBM50347132(CHEMBL1797239)
Affinity DataIC50:  3.03E+5nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate after 10 mins by Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Putra Malaysia

Curated by ChEMBL
LigandPNGBDBM50347128(CHEMBL1797235)
Affinity DataIC50:  3.42E+5nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate after 10 mins by Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Putra Malaysia

Curated by ChEMBL
LigandPNGBDBM50347131(CHEMBL1797238)
Affinity DataIC50:  3.58E+5nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate after 10 mins by Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed