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Found 30 with Last Name = 'akiyama' and Initial = 'h'
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221566(4-chloro-3-(5-methyl-3-(4-(2-(pyrrolidin-1-yl)etho...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of YESMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50193874(7-(2,6-dimethylphenyl)-5-methyl-N-(4-(2-(pyrrolidi...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of YESMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221553(4-(7-(2-chloro-5-hydroxyphenyl)-5-methylbenzo[e][1...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of YESMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221547(4-chloro-3-(5-methyl-3-(4-(3-(pyrrolidin-1-yl)prop...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221556(4-chloro-3-(5-methyl-3-(4-(piperidin-4-ylsulfonyl)...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221566(4-chloro-3-(5-methyl-3-(4-(2-(pyrrolidin-1-yl)etho...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221566(4-chloro-3-(5-methyl-3-(4-(2-(pyrrolidin-1-yl)etho...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221547(4-chloro-3-(5-methyl-3-(4-(3-(pyrrolidin-1-yl)prop...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221553(4-(7-(2-chloro-5-hydroxyphenyl)-5-methylbenzo[e][1...)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221563((4-(7-(2-chloro-5-hydroxyphenyl)-5-methylbenzo[e][...)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221556(4-chloro-3-(5-methyl-3-(4-(piperidin-4-ylsulfonyl)...)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of YESMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221553(4-(7-(2-chloro-5-hydroxyphenyl)-5-methylbenzo[e][1...)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221547(4-chloro-3-(5-methyl-3-(4-(3-(pyrrolidin-1-yl)prop...)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of YESMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221556(4-chloro-3-(5-methyl-3-(4-(piperidin-4-ylsulfonyl)...)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221563((4-(7-(2-chloro-5-hydroxyphenyl)-5-methylbenzo[e][...)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of YESMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50193874(7-(2,6-dimethylphenyl)-5-methyl-N-(4-(2-(pyrrolidi...)
Affinity DataIC50:  7nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50198782(([7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]tri...)
Affinity DataIC50:  10nMAssay Description:Inhibition of YESMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50198782(([7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]tri...)
Affinity DataIC50:  14nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50198813(7-(2-chlorophenyl)-5-methyl-N-(4-(2-(pyrrolidin-1-...)
Affinity DataIC50:  22nMAssay Description:Inhibition of YESMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50198813(7-(2-chlorophenyl)-5-methyl-N-(4-(2-(pyrrolidin-1-...)
Affinity DataIC50:  35nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50198805(5-methyl-7-phenyl-N-(4-(2-(pyrrolidin-1-yl)ethoxy)...)
Affinity DataIC50:  110nMAssay Description:Inhibition of YESMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50198782(([7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]tri...)
Affinity DataIC50:  130nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50198805(5-methyl-7-phenyl-N-(4-(2-(pyrrolidin-1-yl)ethoxy)...)
Affinity DataIC50:  340nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50198805(5-methyl-7-phenyl-N-(4-(2-(pyrrolidin-1-yl)ethoxy)...)
Affinity DataIC50:  530nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221563((4-(7-(2-chloro-5-hydroxyphenyl)-5-methylbenzo[e][...)
Affinity DataIC50:  530nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50193874(7-(2,6-dimethylphenyl)-5-methyl-N-(4-(2-(pyrrolidi...)
Affinity DataIC50:  560nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50198813(7-(2-chlorophenyl)-5-methyl-N-(4-(2-(pyrrolidin-1-...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50587264(CHEMBL5077912)
Affinity DataEC50: >125nMAssay Description:Agonist activity at PR in human T47D cells using p-nitrophenyl phosphate as substrate assessed as induction of alkaline phosphatase activity incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50587263(NORGESTOMET | Norgestomet | SC-21009)
Affinity DataEC50:  4.5nMAssay Description:Agonist activity at PR in human T47D cells using p-nitrophenyl phosphate as substrate assessed as induction of alkaline phosphatase activity incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM8903((1S,2R,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltet...)
Affinity DataEC50:  0.180nMAssay Description:Agonist activity at PR in human T47D cells using p-nitrophenyl phosphate as substrate assessed as induction of alkaline phosphatase activity incubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank