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Found 59 with Last Name = 'alber' and Initial = 't'
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis)
University Of California Berkeley

LigandPNGBDBM26104(5-{2-cyclohexyl-4-[4-fluoro-3-(trifluoromethyl)phe...)
Affinity DataKi:  220nM ΔG°:  -37.6kJ/molepH: 7.4 T: 2°CAssay Description:The reaction was started by addition of pNPP substrate, and reaction progress was monitored at 405 nm. The initial rate data collected was used for d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis)
University Of California Berkeley

LigandPNGBDBM26103(5-{4-[4-fluoro-3-(trifluoromethyl)phenyl]-2-(propa...)
Affinity DataKi:  500nM ΔG°:  -35.6kJ/molepH: 7.4 T: 2°CAssay Description:The reaction was started by addition of pNPP substrate, and reaction progress was monitored at 405 nm. The initial rate data collected was used for d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis)
University Of California Berkeley

LigandPNGBDBM26102(5-[2-(propan-2-yl)-4-[3-(trifluoromethyl)phenyl]ph...)
Affinity DataKi:  850nM ΔG°:  -34.3kJ/molepH: 7.4 T: 2°CAssay Description:The reaction was started by addition of pNPP substrate, and reaction progress was monitored at 405 nm. The initial rate data collected was used for d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312261((4-(4-bromo-3,5-bis(trifluoromethyl)phenylcarbamoy...)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis)
University Of California Berkeley

LigandPNGBDBM26101(5-{4-[3-(trifluoromethyl)phenyl]phenyl}-1,2-oxazol...)
Affinity DataKi:  2.50E+3nM ΔG°:  -31.7kJ/molepH: 7.4 T: 2°CAssay Description:The reaction was started by addition of pNPP substrate, and reaction progress was monitored at 405 nm. The initial rate data collected was used for d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312266((4-(3-(3,5-bis(trifluoromethyl)phenyl)ureido)pheny...)
Affinity DataKi:  3.10E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312260((4-(3,5-bis(trifluoromethyl)phenylcarbamoyl)phenyl...)
Affinity DataKi:  3.30E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312259((4-(4-bromo-3-(trifluoromethyl)phenylcarbamoyl)phe...)
Affinity DataKi:  4.90E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312258((4-(4-chloro-3-(trifluoromethyl)phenylcarbamoyl)ph...)
Affinity DataKi:  6.00E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
University Of California Berkeley

LigandPNGBDBM26104(5-{2-cyclohexyl-4-[4-fluoro-3-(trifluoromethyl)phe...)
Affinity DataKi:  7.70E+3nM ΔG°:  -28.9kJ/molepH: 7.4 T: 2°CAssay Description:The reaction was started by addition of pNPP substrate, and reaction progress was monitored at 405 nm. The initial rate data collected was used for d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis)
University Of California Berkeley

LigandPNGBDBM26099(5-{4-[3-(trifluoromethyl)phenyl]phenyl}-1,2-thiazo...)
Affinity DataKi:  8.80E+3nM ΔG°:  -28.6kJ/molepH: 7.4 T: 2°CAssay Description:The reaction was started by addition of pNPP substrate, and reaction progress was monitored at 405 nm. The initial rate data collected was used for d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312256((4-(4-bromophenylcarbamoyl)phenyl)difluoromethylph...)
Affinity DataKi:  1.03E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312252(CHEMBL1080488 | difluoro(4-(3-(trifluoromethyl)phe...)
Affinity DataKi:  1.07E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312257(CHEMBL1080667 | difluoro(4-(4-fluoro-3-(trifluorom...)
Affinity DataKi:  1.14E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50312261((4-(4-bromo-3,5-bis(trifluoromethyl)phenylcarbamoy...)
Affinity DataKi:  1.48E+4nMAssay Description:Inhibition of human HCPTPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312255((4-(4-chlorophenylcarbamoyl)phenyl)difluoromethylp...)
Affinity DataKi:  1.68E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312251((4-(3-bromophenylcarbamoyl)phenyl)difluoromethylph...)
Affinity DataKi:  1.82E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312254(CHEMBL1080494 | difluoro(4-(4-(trifluoromethyl)phe...)
Affinity DataKi:  1.85E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
University Of California Berkeley

LigandPNGBDBM26104(5-{2-cyclohexyl-4-[4-fluoro-3-(trifluoromethyl)phe...)
Affinity DataKi:  2.14E+4nM ΔG°:  -26.4kJ/molepH: 7.4 T: 2°CAssay Description:The reaction was started by addition of pNPP substrate, and reaction progress was monitored at 405 nm. The initial rate data collected was used for d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312253(CHEMBL1075857 | difluoro(4-(4-fluorophenylcarbamoy...)
Affinity DataKi:  2.27E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312244(CHEMBL1080018 | difluoro(4-(phenylcarbamoyl)phenyl...)
Affinity DataKi:  2.40E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312243(CHEMBL1080017 | difluoro(4-(thiazol-2-ylcarbamoyl)...)
Affinity DataKi:  3.30E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312250((4-(3-chlorophenylcarbamoyl)phenyl)difluoromethylp...)
Affinity DataKi:  3.49E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312249(CHEMBL1080201 | difluoro(4-(3-fluorophenylcarbamoy...)
Affinity DataKi:  4.18E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312242((4-(benzylcarbamoyl)phenyl)difluoromethylphosphoni...)
Affinity DataKi:  4.31E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312248((4-(2-bromophenylcarbamoyl)phenyl)difluoromethylph...)
Affinity DataKi:  4.46E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312241(CHEMBL1081937 | difluoro(4-(2,2,2-trifluoroethylca...)
Affinity DataKi:  4.97E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM26104(5-{2-cyclohexyl-4-[4-fluoro-3-(trifluoromethyl)phe...)
Affinity DataKi: >5.00E+4nM ΔG°: >-24.3kJ/molepH: 7.4 T: 2°CAssay Description:The reaction was started by addition of pNPP substrate, and reaction progress was monitored at 405 nm. The initial rate data collected was used for d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
University Of California Berkeley

LigandPNGBDBM26104(5-{2-cyclohexyl-4-[4-fluoro-3-(trifluoromethyl)phe...)
Affinity DataKi: >5.00E+4nM ΔG°: >-24.3kJ/molepH: 7.4 T: 2°CAssay Description:The reaction was started by addition of pNPP substrate, and reaction progress was monitored at 405 nm. The initial rate data collected was used for d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
University Of California Berkeley

LigandPNGBDBM26104(5-{2-cyclohexyl-4-[4-fluoro-3-(trifluoromethyl)phe...)
Affinity DataKi: >5.00E+4nM ΔG°: >-24.3kJ/molepH: 7.4 T: 2°CAssay Description:The reaction was started by addition of pNPP substrate, and reaction progress was monitored at 405 nm. The initial rate data collected was used for d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312247(CHEMBL1075838 | difluoro(4-(2-(trifluoromethyl)phe...)
Affinity DataKi:  5.48E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312240(CHEMBL1081936 | difluoro(4-(phenethylcarbamoyl)phe...)
Affinity DataKi:  6.16E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312231((4-benzamidophenyl)difluoromethylphosphonic acid |...)
Affinity DataKi:  6.55E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312246((4-(2-chlorophenylcarbamoyl)phenyl)difluoromethylp...)
Affinity DataKi:  6.80E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312239((4-(cyclopentylcarbamoyl)phenyl)difluoromethylphos...)
Affinity DataKi:  7.24E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312230(CHEMBL1081583 | difluoro(4-nitrophenyl)methylphosp...)
Affinity DataKi:  7.54E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312234((2-benzyl-2H-indazol-5-yl)difluoromethylphosphonic...)
Affinity DataKi:  8.44E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312229((4-bromophenyl)difluoromethylphosphonic acid | CHE...)
Affinity DataKi:  9.23E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
University Of California Berkeley

LigandPNGBDBM50312261((4-(4-bromo-3,5-bis(trifluoromethyl)phenylcarbamoy...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human VHRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
University Of California Berkeley

LigandPNGBDBM50312261((4-(4-bromo-3,5-bis(trifluoromethyl)phenylcarbamoy...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human CD45More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
University Of California Berkeley

LigandPNGBDBM50312261((4-(4-bromo-3,5-bis(trifluoromethyl)phenylcarbamoy...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human LARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
University Of California Berkeley

LigandPNGBDBM50312261((4-(4-bromo-3,5-bis(trifluoromethyl)phenylcarbamoy...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human TCPTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50312261((4-(4-bromo-3,5-bis(trifluoromethyl)phenylcarbamoy...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50312261((4-(4-bromo-3,5-bis(trifluoromethyl)phenylcarbamoy...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human PtpBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312265(CHEMBL1081955 | difluoro(4-(N-phenylsulfamoyl)phen...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312264(CHEMBL1079845 | difluoro(4-(phenoxymethyl)phenyl)m...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312263(CHEMBL1075973 | difluoro(4-((phenylamino)methyl)ph...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312262(CHEMBL1075905 | difluoro(4-(methyl(phenyl)carbamoy...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312226(4-(difluoro(phosphono)methyl)benzoic acid | CHEMBL...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312227(CHEMBL1081060 | difluoro(4-(2-oxo-2-(phenylamino)e...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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