Compile Data Set for Download or QSAR
maximum 50k data
Found 44 with Last Name = 'alcaraz' and Initial = 'mj'
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universidad De Murcia

Curated by ChEMBL
LigandPNGBDBM50250921(CHEMBL518103 | isaindigotone)
Affinity DataIC50:  40nMAssay Description:Inhibition of 5LO-mediated LTB4 production in human neutrophils by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universidad De Murcia

Curated by ChEMBL
LigandPNGBDBM50250926(1-ethyl-6-((3-fluoro-5-(4-methoxytetrahydro-2H-pyr...)
Affinity DataIC50:  60nMAssay Description:Inhibitory concentration required against 5-lipoxygenase activity in intact cells of human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universidad De Murcia

Curated by ChEMBL
LigandPNGBDBM50250946(3-(4'-Acetoxy-3',5'-dimethoxy)benzylidene-1,2-dihy...)
Affinity DataIC50:  60nMAssay Description:Inhibition of 5LO-mediated LTB4 production in human neutrophils by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universidad De Murcia

Curated by ChEMBL
LigandPNGBDBM50250926(1-ethyl-6-((3-fluoro-5-(4-methoxytetrahydro-2H-pyr...)
Affinity DataIC50:  90nMAssay Description:Inhibitory concentration required against 5-lipoxygenase activity in cytosolic fractions of human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universidad De Murcia

Curated by ChEMBL
LigandPNGBDBM50250926(1-ethyl-6-((3-fluoro-5-(4-methoxytetrahydro-2H-pyr...)
Affinity DataIC50:  90nMAssay Description:Inhibition of 5LO-mediated LTB4 production in human neutrophils by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Apis mellifera)
Universit£

Curated by ChEMBL
LigandPNGBDBM50066343(5-Hydroxy-4-[6-hydroxy-5-((2E,6E)-3,7,11-trimethyl...)
Affinity DataIC50:  500nMAssay Description:Inhibitory activity against bee secretory Phospholipase A2 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Apis mellifera)
Universit£

Curated by ChEMBL
LigandPNGBDBM50259941(CHEMBL470339 | Petrosaspongiolide M)
Affinity DataIC50:  600nMAssay Description:Inhibition of bee venom secretory PLA2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50066343(5-Hydroxy-4-[6-hydroxy-5-((2E,6E)-3,7,11-trimethyl...)
Affinity DataIC50:  900nMAssay Description:Inhibitory activity against human synovial recombinant Phospholipase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50259952(CHEMBL480874 | cacospongionolide E)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human synovial group2 sPLA2 by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50259941(CHEMBL470339 | Petrosaspongiolide M)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human synovial secretory PLA2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Apis mellifera)
Universit£

Curated by ChEMBL
LigandPNGBDBM50066342(5-Hydroxy-4-[5-((2E,6E)-3,7,11-trimethyl-dodeca-2,...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibitory activity against bee secretory Phospholipase A2 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Apis mellifera)
Universit£

Curated by ChEMBL
LigandPNGBDBM50259951(CHEMBL480681 | cacospongionolide)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of bee venom group3 sPLA2 by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Apis mellifera)
Universit£

Curated by ChEMBL
LigandPNGBDBM50259951(CHEMBL480681 | cacospongionolide)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of bee venom group3 sPLA2 by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50259951(CHEMBL480681 | cacospongionolide)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human synovial group2 sPLA2 by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universidad De Valencia

Curated by ChEMBL
LigandPNGBDBM50029593(CHEMBL7162 | N-(2-(cyclohexyloxy)-4-nitrophenyl)me...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibitory concentration required against COX-2 activity in intact human monocytesMore data for this Ligand-Target Pair
TargetAcidic phospholipase A2 2(Naja naja)
Istituto Per La Chimica Di Molecole Di Interesse Biologico Cnr

Curated by ChEMBL
LigandPNGBDBM50259951(CHEMBL480681 | cacospongionolide)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of Naja naja venom group1 sPLA2 at 10 uM by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universidad De Murcia

Curated by ChEMBL
LigandPNGBDBM50070261((E)-3-(2-Chloro-quinolin-3-yl)-1-(2,4-dimethyl-fur...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibitory concentration required against 5-lipoxygenase activity in cytosolic fractions of human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50259943((1R,3R,4aR,4bS,10aS,12aS)-3-(2-hydroxy-5-oxo-2,5-d...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of human synovial secretory PLA2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50259942(CHEMBL470340 | Petrosaspongiolide P)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of human synovial secretory PLA2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50250399(5-Hydroxy-4-{(R)-6-hydroxy-5-[(E)-4-methyl-6-(2,6,...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of human synovial group2 sPLA2 by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50250399(5-Hydroxy-4-{(R)-6-hydroxy-5-[(E)-4-methyl-6-(2,6,...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of human synovial secretory PLA2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50250399(5-Hydroxy-4-{(R)-6-hydroxy-5-[(E)-4-methyl-6-(2,6,...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibitory activity against human synovial recombinant Phospholipase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universidad De Murcia

Curated by ChEMBL
LigandPNGBDBM50070263((E)-3-(2-Chloro-quinolin-3-yl)-1-(4-fluoro-phenyl)...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibitory concentration required against 5-lipoxygenase activity in cytosolic fractions of human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universidad De Murcia

Curated by ChEMBL
LigandPNGBDBM50070260((E)-1-(3,4-Dichloro-phenyl)-3-furan-2-yl-propenone...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibitory concentration required against 5-lipoxygenase activity in cytosolic fractions of human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50066342(5-Hydroxy-4-[5-((2E,6E)-3,7,11-trimethyl-dodeca-2,...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibitory activity against human synovial recombinant Phospholipase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50377908(CACOSPONGIONOLIDE B)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of human synovial group2 sPLA2 by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universidad De Murcia

Curated by ChEMBL
LigandPNGBDBM50070259((E)-1-(4-Bromo-phenyl)-3-(2,3-dimethoxy-phenyl)-pr...)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibitory concentration required against 5-lipoxygenase activity in cytosolic fractions of human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Apis mellifera)
Universit£

Curated by ChEMBL
LigandPNGBDBM50250399(5-Hydroxy-4-{(R)-6-hydroxy-5-[(E)-4-methyl-6-(2,6,...)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of bee venom group3 sPLA2 by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Apis mellifera)
Universit£

Curated by ChEMBL
LigandPNGBDBM50250399(5-Hydroxy-4-{(R)-6-hydroxy-5-[(E)-4-methyl-6-(2,6,...)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of bee venom secretory PLA2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Apis mellifera)
Universit£

Curated by ChEMBL
LigandPNGBDBM50250399(5-Hydroxy-4-{(R)-6-hydroxy-5-[(E)-4-methyl-6-(2,6,...)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibitory activity against bee secretory Phospholipase A2 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Rattus norvegicus)
Istituto Per La Chimica Di Molecole Di Interesse Biologico Cnr

Curated by ChEMBL
LigandPNGBDBM50259952(CHEMBL480874 | cacospongionolide E)
Affinity DataIC50:  7.80E+3nMAssay Description:Inhibition of rat air pouch group2 sPLA2 by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcidic phospholipase A2 2(Naja naja)
Istituto Per La Chimica Di Molecole Di Interesse Biologico Cnr

Curated by ChEMBL
LigandPNGBDBM50250399(5-Hydroxy-4-{(R)-6-hydroxy-5-[(E)-4-methyl-6-(2,6,...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of Naja naja venom group1 sPLA2 at 10 uM by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Rattus norvegicus)
Istituto Per La Chimica Di Molecole Di Interesse Biologico Cnr

Curated by ChEMBL
LigandPNGBDBM50259951(CHEMBL480681 | cacospongionolide)
Affinity DataIC50:  2.18E+4nMAssay Description:Inhibition of rat air pouch group2 sPLA2 at 10 uM by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Apis mellifera)
Universit£

Curated by ChEMBL
LigandPNGBDBM50377908(CACOSPONGIONOLIDE B)
Affinity DataIC50:  3.54E+4nMAssay Description:Inhibition of bee venom group3 sPLA2 at 10 uM by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Rattus norvegicus)
Istituto Per La Chimica Di Molecole Di Interesse Biologico Cnr

Curated by ChEMBL
LigandPNGBDBM50377908(CACOSPONGIONOLIDE B)
Affinity DataIC50:  3.69E+4nMAssay Description:Inhibition of rat air pouch group2 sPLA2 at 10 uM by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Rattus norvegicus)
Istituto Per La Chimica Di Molecole Di Interesse Biologico Cnr

Curated by ChEMBL
LigandPNGBDBM50250399(5-Hydroxy-4-{(R)-6-hydroxy-5-[(E)-4-methyl-6-(2,6,...)
Affinity DataIC50:  3.84E+4nMAssay Description:Inhibition of rat air pouch group2 sPLA2 at 10 uM by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Apis mellifera)
Universit£

Curated by ChEMBL
LigandPNGBDBM50250399(5-Hydroxy-4-{(R)-6-hydroxy-5-[(E)-4-methyl-6-(2,6,...)
Affinity DataIC50:  6.25E+4nMAssay Description:Inhibition of bee venom group3 sPLA2 at 10 uM by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Rattus norvegicus)
Istituto Per La Chimica Di Molecole Di Interesse Biologico Cnr

Curated by ChEMBL
LigandPNGBDBM50259952(CHEMBL480874 | cacospongionolide E)
Affinity DataIC50:  6.51E+4nMAssay Description:Inhibition of rat air pouch group2 sPLA2 at 10 uM by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50377908(CACOSPONGIONOLIDE B)
Affinity DataIC50:  8.67E+4nMAssay Description:Inhibition of human synovial group2 sPLA2 at 10 uM by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50259951(CHEMBL480681 | cacospongionolide)
Affinity DataIC50:  9.07E+4nMAssay Description:Inhibition of human synovial group2 sPLA2 at 10 uM by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50250399(5-Hydroxy-4-{(R)-6-hydroxy-5-[(E)-4-methyl-6-(2,6,...)
Affinity DataIC50:  9.32E+4nMAssay Description:Inhibition of human synovial group2 sPLA2 at 10 uM by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Apis mellifera)
Universit£

Curated by ChEMBL
LigandPNGBDBM50259952(CHEMBL480874 | cacospongionolide E)
Affinity DataIC50:  9.48E+4nMAssay Description:Inhibition of bee venom group3 sPLA2 at 10 uM by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Apis mellifera)
Universit£

Curated by ChEMBL
LigandPNGBDBM50259952(CHEMBL480874 | cacospongionolide E)
Affinity DataIC50:  9.48E+4nMAssay Description:Inhibition of bee venom group3 sPLA2 at 10 uM by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50259952(CHEMBL480874 | cacospongionolide E)
Affinity DataIC50:  9.67E+4nMAssay Description:Inhibition of human synovial group2 sPLA2 at 10 uM by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed