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Found 164 with Last Name = 'alfei' and Initial = 's'
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50161134(4-(aminomethyl)-N-ethyl-5-[ethyl(methyl)-lambda~5~...)
Affinity DataIC50:  20nMAssay Description:Inhibition of benzylamine binding to Benzylamine oxidase of porcine serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive amine oxidase [copper-containing](Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50161146(4-(aminomethyl)-5-(dimethyl-lambda~5~-azanyl)-N-me...)
Affinity DataIC50:  61nMAssay Description:Inhibition of putrescine binding to against Diamine oxidase of porcine kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50161149(4-(aminomethyl)-N-isopropyl-5-[isopropyl(methyl)-l...)
Affinity DataIC50: >100nMAssay Description:Inhibition of benzylamine binding to Benzylamine oxidase of porcine serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive amine oxidase [copper-containing](Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50161153(4-(aminomethyl)-N-methyl-5-(methyl-lambda~5~-azany...)
Affinity DataIC50:  120nMAssay Description:Inhibition of putrescine binding to against Diamine oxidase of porcine kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50370602(CHEMBL538353)
Affinity DataIC50:  130nMAssay Description:Inhibition of benzylamine binding to Benzylamine oxidase of porcine serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50161150(4-{[4-(aminomethyl)-5-(4-hydroxybutoxy)pyridin-3-y...)
Affinity DataIC50:  150nMAssay Description:Inhibition of benzylamine binding to Benzylamine oxidase of porcine serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University Of Genova

Curated by ChEMBL
LigandPNGBDBM50577800(CHEMBL4853419)
Affinity DataIC50:  160nMAssay Description:Inhibition of C-terminal 6His-tagged human PDE4D3 expressed in baculovirus infected Sf9 insect cells assessed as reduction in 5'-AMP formation using ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive amine oxidase [copper-containing](Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50161135(4-(aminomethyl)-N-methylpyridin-3-amine dihydrochl...)
Affinity DataIC50:  160nMAssay Description:Inhibition of putrescine binding to against Diamine oxidase of porcine kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50161143((3,5-diethoxypyridin-4-yl)methylamine dihydrochlor...)
Affinity DataIC50:  170nMAssay Description:Inhibition of benzylamine binding to Benzylamine oxidase of porcine serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive amine oxidase [copper-containing](Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50161138(4-(aminomethyl)pyridin-3-amine dihydrochloride | C...)
Affinity DataIC50:  300nMAssay Description:Inhibition of putrescine binding to against Diamine oxidase of porcine kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50161146(4-(aminomethyl)-5-(dimethyl-lambda~5~-azanyl)-N-me...)
Affinity DataIC50:  440nMAssay Description:Inhibition of benzylamine binding to Benzylamine oxidase of porcine serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University Of Genova

Curated by ChEMBL
LigandPNGBDBM50577801(CHEMBL4862157)
Affinity DataIC50:  470nMAssay Description:Inhibition of C-terminal 6His-tagged human PDE4D3 expressed in baculovirus infected Sf9 insect cells assessed as reduction in 5'-AMP formation using ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive amine oxidase [copper-containing](Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50161132(4-(aminomethyl)-N-ethylpyridin-3-amine dihydrochlo...)
Affinity DataIC50:  500nMAssay Description:Inhibition of putrescine binding to against Diamine oxidase of porcine kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPrimary amine oxidase(Pisum sativum)
Universit£

Curated by ChEMBL
LigandPNGBDBM50161135(4-(aminomethyl)-N-methylpyridin-3-amine dihydrochl...)
Affinity DataIC50:  710nMAssay Description:Inhibition of putrescine binding to pea seedling amine oxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University Of Genova

Curated by ChEMBL
LigandPNGBDBM50577804(CHEMBL4852484)
Affinity DataIC50:  720nMAssay Description:Inhibition of C-terminal 6His-tagged human PDE4D3 expressed in baculovirus infected Sf9 insect cells assessed as reduction in 5'-AMP formation using ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive amine oxidase [copper-containing](Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50161149(4-(aminomethyl)-N-isopropyl-5-[isopropyl(methyl)-l...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of putrescine binding to against Diamine oxidase of porcine kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University Of Genova

Curated by ChEMBL
LigandPNGBDBM50577805(CHEMBL4876286)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of C-terminal 6His-tagged human PDE4D3 expressed in baculovirus infected Sf9 insect cells assessed as reduction in 5'-AMP formation using ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50370601(CHEMBL539362)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of benzylamine binding to Benzylamine oxidase of porcine serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50161153(4-(aminomethyl)-N-methyl-5-(methyl-lambda~5~-azany...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of benzylamine binding to Benzylamine oxidase of porcine serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50161132(4-(aminomethyl)-N-ethylpyridin-3-amine dihydrochlo...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of benzylamine binding to Benzylamine oxidase of porcine serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive amine oxidase [copper-containing](Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50161134(4-(aminomethyl)-N-ethyl-5-[ethyl(methyl)-lambda~5~...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of putrescine binding to against Diamine oxidase of porcine kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University Of Genova

Curated by ChEMBL
LigandPNGBDBM50577801(CHEMBL4862157)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of C-terminal 6His-tagged human PDE4D catalytic domain (244 to 578 residues) expressed in Escherichia coli BL21(DE3) pLysS cells assessed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University Of Genova

Curated by ChEMBL
LigandPNGBDBM50577800(CHEMBL4853419)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of C-terminal 6His-tagged human PDE4D catalytic domain (244 to 578 residues) expressed in Escherichia coli BL21(DE3) pLysS cells assessed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50161136(2-{[4-(aminomethyl)-5-(2-hydroxyethoxy)pyridin-3-y...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of benzylamine binding to Benzylamine oxidase of porcine serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University Of Genova

Curated by ChEMBL
LigandPNGBDBM50577803(CHEMBL4868872)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of C-terminal 6His-tagged human PDE4D3 expressed in baculovirus infected Sf9 insect cells assessed as reduction in 5'-AMP formation using ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University Of Genova

Curated by ChEMBL
LigandPNGBDBM50577805(CHEMBL4876286)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of C-terminal 6His-tagged human PDE4D catalytic domain (244 to 578 residues) expressed in Escherichia coli BL21(DE3) pLysS cells assessed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University Of Genova

Curated by ChEMBL
LigandPNGBDBM50577803(CHEMBL4868872)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of C-terminal 6His-tagged human PDE4D catalytic domain (244 to 578 residues) expressed in Escherichia coli BL21(DE3) pLysS cells assessed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive amine oxidase [copper-containing](Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50161147(4-(aminomethyl)-N-cyclopropylpyridin-3-amine dihyd...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of putrescine binding to against Diamine oxidase of porcine kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50161131(CHEMBL536951 | [3-(benzyloxy)-5-ethoxypyridin-4-yl...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of benzylamine binding to Benzylamine oxidase of porcine serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50161140(4-(aminomethyl)-N-(cyclohexylmethyl)pyridin-3-amin...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of benzylamine binding to Benzylamine oxidase of porcine serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University Of Genova

Curated by ChEMBL
LigandPNGBDBM50577804(CHEMBL4852484)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of C-terminal 6His-tagged human PDE4D catalytic domain (244 to 578 residues) expressed in Escherichia coli BL21(DE3) pLysS cells assessed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50161135(4-(aminomethyl)-N-methylpyridin-3-amine dihydrochl...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of benzylamine binding to Benzylamine oxidase of porcine serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPrimary amine oxidase(Pisum sativum)
Universit£

Curated by ChEMBL
LigandPNGBDBM50161132(4-(aminomethyl)-N-ethylpyridin-3-amine dihydrochlo...)
Affinity DataIC50:  9.30E+3nMAssay Description:Inhibition of putrescine binding to Pea seedling amine oxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive amine oxidase [copper-containing](Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50161151(4-(aminomethyl)-5-[methyl(propyl)-lambda~5~-azanyl...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of putrescine binding to against Diamine oxidase of porcine kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50161151(4-(aminomethyl)-5-[methyl(propyl)-lambda~5~-azanyl...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory concentration for rat liver Monoamine oxidase A using 5-hydroxytryptamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University Of Genova

Curated by ChEMBL
LigandPNGBDBM50299569(3-(cyclopentyloxy)-4-methoxybenzaldehyde O-[2-(2,6...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of C-terminal 6His-tagged human PDE4D3 expressed in baculovirus infected Sf9 insect cells assessed as reduction in 5'-AMP formation using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University Of Genova

Curated by ChEMBL
LigandPNGBDBM50577802(CHEMBL4862518)
Affinity DataIC50:  1.12E+4nMAssay Description:Inhibition of C-terminal 6His-tagged human PDE4D3 expressed in baculovirus infected Sf9 insect cells assessed as reduction in 5'-AMP formation using ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University Of Genova

Curated by ChEMBL
LigandPNGBDBM50299569(3-(cyclopentyloxy)-4-methoxybenzaldehyde O-[2-(2,6...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of C-terminal 6His-tagged human PDE4D catalytic domain (244 to 578 residues) expressed in Escherichia coli BL21(DE3) pLysS cells assessed ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50161139(4-(aminomethyl)-N-cyclopentylpyridin-3-amine dihyd...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of benzylamine binding to Benzylamine oxidase of porcine serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive amine oxidase [copper-containing](Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50161152(4-(aminomethyl)-N-isopropylpyridin-3-amine dihydro...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of putrescine binding to Diamine oxidase of porcine kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive amine oxidase [copper-containing](Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50161148(4-(aminomethyl)-N-cyclohexylpyridin-3-amine dihydr...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of putrescine binding to against Diamine oxidase of porcine kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50161138(4-(aminomethyl)pyridin-3-amine dihydrochloride | C...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of benzylamine binding to Benzylamine oxidase of porcine serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPrimary amine oxidase(Pisum sativum)
Universit£

Curated by ChEMBL
LigandPNGBDBM50161146(4-(aminomethyl)-5-(dimethyl-lambda~5~-azanyl)-N-me...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of putrescine binding to Pea seedling amine oxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive amine oxidase [copper-containing](Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50161133(4-(aminomethyl)-N-cycloheptylpyridin-3-amine dihyd...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of putrescine binding to against Diamine oxidase of porcine kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive amine oxidase [copper-containing](Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50161139(4-(aminomethyl)-N-cyclopentylpyridin-3-amine dihyd...)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of putrescine binding to against Diamine oxidase of porcine kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50161151(4-(aminomethyl)-5-[methyl(propyl)-lambda~5~-azanyl...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibitory concentration for rat liver Monoamine oxidase B using beta-phenylethylamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University Of Genova

Curated by ChEMBL
LigandPNGBDBM50577802(CHEMBL4862518)
Affinity DataIC50:  3.31E+4nMAssay Description:Inhibition of C-terminal 6His-tagged human PDE4D catalytic domain (244 to 578 residues) expressed in Escherichia coli BL21(DE3) pLysS cells assessed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50161146(4-(aminomethyl)-5-(dimethyl-lambda~5~-azanyl)-N-me...)
Affinity DataIC50:  4.40E+4nMAssay Description:Inhibitory concentration for rat liver Monoamine oxidase A using 5-hydroxytryptamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive amine oxidase [copper-containing](Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50161140(4-(aminomethyl)-N-(cyclohexylmethyl)pyridin-3-amin...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of putrescine binding to against Diamine oxidase of porcine kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisomal primary amine oxidase(Pichia angusta)
Universit£

Curated by ChEMBL
LigandPNGBDBM50161135(4-(aminomethyl)-N-methylpyridin-3-amine dihydrochl...)
Affinity DataIC50:  5.30E+4nMAssay Description:Inhibition of phenylethylamine binding to Hansenula polymorpha amine oxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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